ORIGINAL_ARTICLE
A Comparative Study of Some Nuts And Seeds Constituents Available in Local Market at Misurata City-Libya
The aim of this study was to estimate and compare some of chemical constituents in nuts and seeds consumed as snacks and available in the local market of Misurata city in Libya. 18 kinds of local and imported raw and roasted nuts and seeds samples were randomly collected from stores distributed across the city, with 3 - 4 replicates of each kind, in order to estimate the concentrations of some chemical components and heavy elements, which were lead (Pb), cadmium (Cd), Iron (Fe), copper (Cu), chromium (Cr), manganese (Mn), cobalt (Co), zinc (Zn), nickel (Ni), moisture, ash, total solids and protein. The dry digestion method was used to prepare the samples for heavy metals determination using Flame Atomic Absorption Spectrometer. Also, moisture, ash and total solids contents were determined, and Kjeldahl method was used to estimate proteins. The results showed that the average concentrations of heavy metals varied significantly with sample kind. The levels of the studied metals were as follows: 0.075 - 1.167, 31.50 - 116.00, 0.325 - 1.325, 9.425- 71.00, 0.025-3.87, 8.325- 24.825, 0.175- 1.250, 0.050- 0.750, 43.00- 98.325 mg/kg, for Co, Zn, Ni, Mn, Pb, Cu, Cr, Cd, and Fe, respectively. Also, levels of moisture contents, ash contents, total solids contents, and protein levels were: 4.0 - 8.5%, 2.0 - 11.39%, 91.5 - 96.0%, and 11.8 - 33.2%, respectively. Most of the obtained results were consistent with the previous studies and within the permissible limits.
https://ijac.journals.pnu.ac.ir/article_7633_3aa971d0fad1a6448eb6c13b284a4241.pdf
2021-03-01
1
9
10.30473/ijac.2021.57619.1180
Nuts
Seeds
Heavy metals
Chemical Constituents
Abdulfattah
Alkherraz
abdo_7979355176@yahoo.co.uk
1
Chemistry Department, Faculty of Science, Misurata University, Misurata, Libya
AUTHOR
Mohammed
Sebsi
elmusllaty@yahoo.com
2
Chemistry Department, Faculty of Science, Misurata University, Misurata, Libya
AUTHOR
Mohamed
Sassi
elmusllaty@gmail.com
3
Chemistry Department, Faculty of Education, Misurata University, Misurata, Libya
AUTHOR
Khaled
Elsherif
elsherif27@yahoo.com
4
Chemistry Department, Faculty of Science, University of Benghazi, Benghazi-Libya
LEAD_AUTHOR
[1] F.B. Hu and M.J. Stampfer, Nut consumption and risk of coronary health disease a review of epidemiologic evidence, Curr. Atheroscler. Rep., 1 (1999) 205- 210.
1
[2] P.M. Kris-Etherton, S. Yu-Poth, J. Sabate, H. Ratcliffe, G. Zhao and T. Etherton, Nuts and their bioactive constituents effects on serum lipids and factors that affects disease risk, Am. J. Clin. Nutr., 70 (1999) 504s – 511s.
2
[3] C. Chen and J. Blumberg, Phytochemical composition of nuts, Asia Pac. J. Clin. Nutr., 17 (2008) 329-32.
3
[4] K. Alexiadou and N. Katsilambros, Nuts: anti-atherogenic food, Eur. J. Intern. Med., 22 (2011) 141-6.
4
[5] R.G.M. de Souza, R.M. Schincaglia, G.D. Pimentel and J.F. Mota, Nuts and Human Health Outcomes: A Systematic Review, Nutrients, 9 (2017) 1311- 1334.
5
[6] L.R. Bordajandi, G. Gomez, E. Abad, J. Rivera, M.D. Fernandez-Baston, J. Blasco, and M.J. Gonzalez, Survey of persistent organochlorine contaminants (PCBs, PCDD/Fs, and PAHs), heavy metals (Cu, Cd, Zn, Pb and Hg) and arsenic in food samples from Huelva Spain: levels and health implications, J. Agric. Food Chem., 52 (2014) 992-1001.
6
[7] U. Celik and J. Oehlenschlager, High contents of cadmium, lead, zinc and copper in popular fishery products sold in Turkish supermarkets, Food Control, 18 (2007) 258-261.
7
[8] G. Davarynejad, M. Zarei and P.T. NAGY, Identification and Quantification of Heavy Metals Concentrations in Pistacia, Not. Sci. Biol., 5 (2013) 438-444.
8
[9] N. Jalbani, T.G. Kazi, M.K. Jamali, M.B. Arain, H.I. Afrid, S.T. Sheerazi and R. Ansari, Application of fractional factorial design and doehlert matrix in the optimization of experimental variables associated with the ultrasonic-assisted acid digestion of chocolate samples for aluminum determination by atomic absorption spectrometry, J. AOAC Int., 90 (2007) 1682- 1688.
9
[10] C. Cabrera, F. Lioris, R. Gimenez, M. Olalla and M. Lopez, Mineral content in legumes and nuts: contribution to the Spanish, dietary intake, Sci. Total Environ., 308 (2003) 1-14.
10
[11] K.M. Elsherif and H.M. Kuss, Direct and Simultaneous Determination of Bismuth, Antimony, and Lead in Biological samples by Multi Element Electrothermal Atomic Absorption Spectrometer, Der Chem. Sin., 3 (2012) 727-736.
11
[12] K.M. Elsherif, R.A. Abu Khater and F.A. Hegaig, Determination of major and minor elements in dairy products produced in Misurata city – Libya, Maghrebian J. Pure Appl. Sci., 3 (2017) 9-17.
12
[13] K.M. Elsherif and H.M. Kuss, Simultaneous Multi-Element Determination of Bismuth (Bi), Antimony (Sb), and Selenium (Se), Adv. Appl. Sci. Res., 3 (2012) 2402-2412.
13
[14] A.M. Alkherraz, O. Hashad and K.M. Elsherif, Heavy metals contents in some commercially available coffee, tea, and cocoa samples in misurata City–Libya, Prog. Chem. Biochem. Res., 2 (2019), 99-107.
14
[15] M.A. Elbagermi, A.A. Bin Haleem and K.M. Elsherif, Physicochemical properties and nutritional values of pasteurized milk and long-life milk: A comparative study, J. Anal. Sci. Appl. Biotechnol., 2 (2020), 38-45.
15
[16] M.A. Elbagermi, A.A. Bin Haleem and K.M. Elsherif, Evaluation of essential and heavy metal levels in pasteurized and long-life cow milk, Int. J. Adv. Chem., 8 (2020) 6-14.
16
[17] S.B. Adeloju, Comparison of Some Wet Digestion and Dry Ashing Methods for Voltammetric Trace Element Analysis, Analyst, 114 (1989) 455-461.
17
[18] Y.L. Liang, T. Qing, S.X. Zhang, K.X. Yin and J.Y. Qin, Determination of Trace Elements in Edible Nuts in the Beijing Market by ICP-MS, Biomed. Environ. Sci., 28 (2015), 449-454.
18
[19] I. Rodushkina, E. Engströma, D. Sörlinb and D. Baxterb, Levels of inorganic constituents in raw nuts and seeds on the Swedish market, Sci. Total Environ., 392 (2008) 290 – 304.
19
[20] H.S. Manzoor, I.H. Bukhari, M. Riaz, N. Rasool, U. Sattar, G. Rehman and Q. Ul Ain, Effect of microwave roasting and storage on the extent of heavy metals present in dry fruits, Int. J. Chem. Biochem. Sci., 3 (2013) 74-82.
20
[21] F. Zhu, L. Qu, W. Fan, M. Qiao, H. Hao and X. Wang, Assessment of heavy metals in some wild edible mushrooms collected from Yunnan Province, China, Environ. Monit. Assess., 179 (2010) 191- 199.
21
[22] R. Moodley, A. Kindness and S.B. Jonnalagadda, Elemental composition and chemical characteristics of five edible nuts (almond, Brazil, pecan, macadamia and walnut) consumed in Southern Africa, J. Environ. Sci. Health, Part B, 42 (2007) 585–591.
22
[23] M. Soylak, H. Colak, O. Turkoglu and M. Dogan, Trace metal content of snacks and appetizers consumed in Turkey, Bull. Environ. Contam. Toxicol., 76 (2006) 436- 441.
23
[24] S.H. Zlotkin and B.E. Buchanan, Manganese Intakes in Intravenously Fed Infants, Biol. Trace Elem. Res., 9 (1986) 271- 280.
24
[25] V. Kamar, R. Dagalp and M. Tastekin, Determination of Heavy Metals in Almonds and Mistletoe as a Parasite Growing on the Almond Tree Using ICP-OES or ICP-MS, Biol. Trace Elem. Res., 185 (2018) 226- 235.
25
[26] E.E. Santosa, D.C. Lauriab and C.L. Silveirac, Assessment of daily intake of trace elements due to consumption of foodstuffs by adult inhabitants of Rio de Janeiro city, Sci. Total Environ., 327 (2004) 69–79.
26
[27] K.H. Chung, K.O. Shin, H.J. Hwang and K. Choi, Chemical composition of nuts and seeds sold in Korea, Nutr. Res. Pract., 7 (2013) 82-88.
27
[28] M. Venkatachalam and S.K. Sathe, Chemical Composition of Selected Edible Nut Seeds, J. Agric. Food Chem., 54 (2006) 4705- 4714.
28
[29] K.M. Mahmoud and R.T. Yasin, Quantitative Analysis of Some Metals in Alomond Kernel in Erbil City, Int. J. Pharma Sci. Res., 7 (2016) 32 – 37.
29
[30] Q.A. Ibraheem, W.S. Ulaiwi and S. Eanas, The bioactivity and nutritional roles of some mineral and nutritive constituents of hazelnut Corylus avellana and walnut Juglans regia, Anbar J. Agric. Sci., 10 (2012) 223-234.
30
ORIGINAL_ARTICLE
Experimental and Theoretical Studies of One Dihydropyridine Derivative as Corrosion Inhibitor in Acidic Media
A new organic compound, namely dihydropyrimido [4,5-b][1,6] naphthyridine-2,4, 6, 8(1H,3H,7H,9H)-tetraones with amino acid moiety (DHPN) was synthesized and characterized by 1H, 13C Nuclear magnetic resonance (NMR) and Fourier transform infrared (FTIR) spectroscopy experiments. DHPN was investigated for the first time as a green inhibitor of mild steel (A105) corrosion in acidic (0.1, 0.5 mol L-1 H2SO4 and HCl) solutions using potentiodynamic polarization technique. The results showed that, inhibition efficiency increased with the inhibitor concentration within the range of 0.95-19 mg L-1. The polarization curves demonstrated that, this compound act as a mixed type inhibitor. The adsorption of the DHPN molecule on the surface of mild steel was found to obey the Langmuir adsorption isotherm. Besides, data processing methods like support vector machine modelling was performed to prove the relationship between inhibitory effect and molecular structure.
https://ijac.journals.pnu.ac.ir/article_7634_7e0dcc541cd5d2778f1e679a79099395.pdf
2021-03-01
10
16
10.30473/ijac.2021.57472.1179
Corrosion Inhibition
Support vector machine
Mild steel
potentiometric polarization
Homa
Shafieekhani
shafieehoma@yahoo.com
1
Department of Chemistry, Payam Noor University, P.O. Box 19395-4697, Tehran, Iran
LEAD_AUTHOR
Somayeh
Karimi
2
Islamic Azad University, Lamerd Branch, P.O. Box 74341-553881, Lamerd, Iran
AUTHOR
Mohammad
Torkashvand
3
College of Engineering, University of Tehran, P.O. Box. 14395-515, Tehran, Iran
AUTHOR
[1] K. Kerkouche, A. Benchettara and S. Amara, Effect of sodium dodecyl benzene sulfonate on the corrosion inhibition of Fe-1Ti-20C alloy in 0.5 M H2SO4, Mater. Chem. Phys. 110 (2008) 26 -33.
1
[2] A.M. Al-Sabagh, H.M. Abd-El-Bary, R.A El-Ghazawy, M.R. Mishrif and B.M. Hussein, Corrosion inhibition efficiency of linear alkyl benzene derivatives for carbon steel pipelines in 1M HCl, Egypt. J. Petro. 20 (2011) 33-45.
2
[3] I.B. Obot, I.B. Onyeachu and A.M. Kumar, Sodium alginate: a promising biopolymer for corrosion protection of API X60 high strength carbon steel in saline medium, Carbohydr. Polym. 178 (2017) 200-208.
3
[4] M.A. Chidiebere, l. Nanna, C.B. Adindu, K.L. Oguzie, B. Okolue and B.I. Onyeachu, Inhibition of acid corrosion of mild steel using Delonix regia leaves extract, Int. Lett. Chem. Phys.Astron. 69 (2016)74-86.
4
[5] S.A. Umoren, M.M. Solomon, I.B. Obot and R.K. Suleiman, Comparative studies on the corrosion inhibition efficacy of ethanolic extracts of date palm leaves and seeds on carbon steel corrosion in 15% HCl solution, J. Adhes. Sci. Technol. 32 (7) (2018)1934-1951.
5
[6] R.H. Albrakaty, N.A. Wazzan and I.B. Obot, Theoretical study of the mechanism of corrosion inhibition of carbon steel in acidic solution by 2-aminobenzothiazole and 2- mercaptobenzothiazole, Int.J. Electrochem. Sci. 13(4) (2018) 3535-3554.
6
[7] M. Yildiz, H.Gerengi, M.M. Solomon, E. Kaya and S.A. Umoren, Influence of 1- butyl-1-methylpiperidinioum tetrfluoroborate on st37 steel dissolution behavior in HCl environment, Chem. Eng.Commun. 205 (4) (2018) 538-548.
7
[8] N.A.Wazzan, I. Obot and S. Kaya, Theoretical modeling and molecular level insights into the corrosion inhibiton activity of 2-amino-1,3,4-thiadiazole and its 5-alkyl derivatives, J. Mol. Liq. 221 (2016) 579-602.
8
[9] R. Kumar, H. Kim, R. Umapathi, O.S. Yadav and G. Singh, Comprehensive adsorption characteristics of a newly synthesized and sustainable anti-corrosion catalyst on mild steel surface exposed to a highly corrosive electrolytic solution, J. Mol. Liq. 268 (2018) 37-48.
9
[10] T. Ramde, S. Rossi and C. Zanella, Inhibition of the Cu65/Zn35 brass corrosion by natural extract of Camellia sinensis, Appl. Surf. Sci.307 (2014) 209-216.
10
[11] A. Zarrouk, B. Hammouti, A. Dafali, M. Bouachrine, H. Zarrok, S. Boukhris and S.S. Al-Deyab, A theoretical study on the inhibition efficiencies of some quinoxalines as corrosion inhibitors of copper in nitric acid, J. Saudi Chem. Soc. 18 (2014) 450-455.
11
[12] S.O. Ajeigbe, N. Basar, H. Maarof, A.M. Al-Fakih, M.A. Hassan and M. Aziz, Evaluation of Alpinia galanga and its active principle, 1'-acetochavicol acetate as eco-friendly corrosion inhibitors on mild steel in acidic medium, J. Mater. Environ. Sci.7 (2017) 2040-2049.
12
[13] A.M. Al-sabagh, H.M. Abd-El-Bary, R.A. El-Ghazawy, M.R. Mishrif and B.M. Hussein, Surface active and thermodynamic properties of some surfactants derived from locally linear and heavy alkyl benzene in relation to corrosion inhibition efficiency, Mater. Corros. 62 (2011) 1015-1030.
13
[14] H. Elmsellem, Y. El Ouadi, M. Mokhtari, H. Steli, A. Aouniti, A.M. Almehdi, I. Abdel-Rahman and H.S. Kusuma, A natural antioxidant and an environmentally friendly inhibitor of mild steel corrosion: a commercial oil of basil, J. Chem.Technol. Metall. 54 (2019) 742-749.
14
[15] P.C. Okafor, V.I. Osabor and E.E. Ebenso, Eco-friendly corrosion inhibitors: inhibitive action of ethanol extracts of Garcinia Kola for the corrosion of mild steel In H2SO4 solutions. Pig. Resin Technol. 36 (2007) 134-140.
15
[16] L. Hamidi, S. Mansouri, K. Oulmi and A. Kareche, The use of amino acids as corrosion inhibitors for metals, Egypt. J. Pet. 27 (2018) 1157-1165.
16
[17] B. El Ibrahimi, A. Jmiai, L. Bazzi and S. El Issami, Amino acids and their derivatives as corrosion inhibitors for metals and alloys, Arab. J. Chem.13 (2020) 740-771.
17
[18] F. Bentiss, B. Mernari, M. Traisnel, H. Vezin and M. Lagrenee, On the relationship between corrosion inhibiting effect and molecular structure of 2, 5-bis (n-pyridyl)-1, 3, 4-thiadiazole derivatives in acidic media: Ac impedance and DFT studies, Corros. Sci. 53 (2011) 487 -495.
18
[19] I. Danaee, M. Gholami, M. Rashvand Avei and M.H. Maddahy, Quantum chemical and experimental investigations on inhibitory behaviour of amino–imino tautomeric equilibrium of 2-aminobenzothiazole on steel corrosion in H2SO4 solution, J. Ind. Eng. Chem. 26(2015) 81–94.
19
[20] A. Karimi, I. Danaee, H. Eskandari and M. Rashvand Avei, Electrochemical investigations on the inhibition behavior and adsorption isotherm of synthesized di- (Resacetophenone)-1, 2-cyclohexandiimine schiff base on the corrosion of steel in 1 M HCl, Prot. Met. Phys. Chem. 51(2015)899–907.
20
[21] I. Danaee and N. Bahramipanah, Thermodynamic and adsorption behavior of N2O4 Schiff base as a corrosion inhibitor for API-5L-X65 steel in HCl solution, Russ. J. Appl. Chem. 89 (2016) 487−497.
21
[22] H.M. Abd El-Lateef, M.S.S. Adam and M.M. Khalaf, Synthesis of polar unique 3d metal-imine complexes of salicylidene anthranilate sodium salt. Homogenous catalytic and corrosion inhibition performance, J. Taiwan. Inst. Chem. Eng. 88 (2018) 286-304.
22
[23] M.S.S. Adam, H.M. Abd El-Lateef and K.A, Soliman, Anionic oxide vanadium Schiff base amino acid complexes as potent inhibitors and as effective catalysts for sulfides oxidation: experimental studies complemented with quantum chemical calculations, J. Mol. Liq. 250 (2018) 307-322.
23
[24] H.M. Abd El Lateef, M. Ismael and I.M.A. Mohamed, Novel Schiff base amino acid as corrosion inhibitors for carbon steel in CO2-saturated 3.5% NaCl solution: Experimental and computational study, Corros. Rev. 33 (2015) 77-79.
24
[25] H.M. Abd El Lateef, Experimental and computational investigation on the corrosion inhibition characteristics of mild steel by some novel synthesized imines in hydrochloric acid solutions, Corros. Sci. 92 (2015) 104-117.
25
[26] H. Elmsellem, T. Harit, A. Aouniti and F. Malek, Adsorption properties and inhibition of mild steel corrosion in 1M HCl solution by some bipyrazolic derivatives: experimental and theoretical investigation, Prot. Met. Phy. Chem. Surf. 51 (2015) 873-884.
26
[27] S. Bashir, H. Lgaz, I.M. Chung and A. Kumar, Potential of venlafaxine in the inhibitor of mild steel corrosion in HCl: insights from experimental and computational studies. Chem. Pap. 73(2019) 2255- 2264.
27
[28] S. Attabi, M. Mokhtari, Y. Taibi, I. Abdel-Rahman, B. Hafez and H. Elmsellem, Electrochemical and tribiological behavior of surface-treated titanium alloy Ti-6Al-4V, J. Bio. Tribo. Corros. 5 (2019)
28
[29] X. Yin and Q. Yuan, A new class of measures for testing independence, Stat. Sinica. In press. (2019). http://www.stat.sinica.edu.tw/statistica
29
[30] N. Parveen, S. Zaidi and M. Danish, Support vector regression (SVR) based adsorption model for Ni (II) ions removal, Ground. Sustain. Dev. 29(2019) 100232.
30
[31] B. Choubin, E. Moradi, M. Golshan, J. Adamowski, F. Sajedi-Hosseini and A. Mosavi, An ensemble prediction of flood susceptibility using multivariate discriminant analysis, classification and regression trees, and support vector machines, Sci. Total. Environ. 651(2019) 2087-2096.
31
[32] A. Ghaffarkhah, M. Afrand, M. Talebkeikhah, A.A. Sehat, M.K. Moraveji, F. Talebkeikhah and M. Arjmand, On evaluation of thermophysical properties of transformer oil-based nanofluids: A comprehensive modelling and experimental study, J. Mol. Liq. 300 (2020) 112249.
32
ORIGINAL_ARTICLE
Optimization of the Nickel Removal Process From Zinc Sulfate Solution Using Central Composite Design of Experiments
Nickel is one of the metallic impurities that should be removed from the electrolyte solution before the electrowinning of zinc. This study investigated the parameters affecting the process of nickel removal in an Iranian zinc smelter plant by the response surface methodology. According to the results of experiments, the optimum condition for removal of nickel was obtained at temperature of 85 °C, the residence time of 60 minutes, zinc powder of 2.5 g/l, mixing speed of 500 rpm, and pH of 5. With regards to the resulting model from the Design-Expert software, the significant parameters were concentration, residence time, and temperature, respectively.
https://ijac.journals.pnu.ac.ir/article_7644_1ea845b07aa9469d05f81067775a15f2.pdf
2021-03-01
17
28
10.30473/ijac.2021.57821.1181
Removal of Nickel
Central Composite Design
Zinc Sulfate Solution
Optimization
Cementation
Pourya
Abbasi
pourya.abbasi1991@gmail.com
1
Department of Chemical Engineering, University of Mohaghegh Ardabili, Ardabil, Iran
AUTHOR
Keyvan
Shayesteh
k.shayesteh@uma.ac.ir
2
Department of Chemical Engineering, University of Mohaghegh Ardabili, Ardabil, Iran
LEAD_AUTHOR
Vahid
Vahidfard
v.vahidfard@gmail.com
3
Department of Chemical Engineering, University of Mohaghegh Ardabili, Ardabil, Iran; Innovation Center, Payame Noor University, Iran
AUTHOR
Mehdi
Hosseini
hosseini.mih@gmail.com
4
Department of Chemistry,Faculty of Basic Science, Ayatollah Boroujerdi University, Boroujerd, Iran
AUTHOR
ORIGINAL_ARTICLE
Molecular Modeling Studies of Triazolyl Thiophenes As CDK5/P25 inhHibitors Using 3D-QSAR and Molecular Docking
Three-dimensional quantitative structure-activity relationship (3D-QSAR) techniques are useful methods for ligand-based drug design by correlating physicochemical descriptors from a set of related compounds to their known molecular activity or molecular property values. A novel clubbed triazolyl thiophene series of cdk5/p25 inhibitors were selected to establish 3D-QSAR models using Comparative molecular field analysis (CoMFA) and Comparative molecular similarity indices analysis (CoMSIA) methods. The optimum CoMFA and CoMSIA models obtained, were statistically significant with cross-validated correlation coefficients r2cv (q2) of 0.539 and 0.558, and conventional correlation coefficients (r2) of 0.980 and 0.967, respectively. A training set containing 88 molecules and a test set containing 24 molecules served to establish the QSAR models. Independent test set validated the external predictive power of both models with predicted correlation coefficients (r2pred) 0.968 and 0.945 for CoMFA and CoMSIA, respectively. Molecular docking was applied to explore the binding mode between the ligand and the receptor. The information obtained from molecular modeling studies may be helpful to design novel CDK5/P25 inhibitors with desired activity.
https://ijac.journals.pnu.ac.ir/article_7788_cf2bec713f28b5914086ddc9019460e2.pdf
2021-03-01
29
38
10.30473/ijac.2021.59304.1189
3D-QSAR
molecular docking
Cdk5/Pp25 Inhibitors
triazolyl thiophene
Alzheimer disease
Zahra
Garkani Nejad
z_garakani@yahoo.com
1
Chemistry Department, Faculty of Science, Shahid Bahonar University of Kerman, Kerman, Iran
LEAD_AUTHOR
Abuozar
Ghanbari
chemabuozar@gmail.com
2
MAPNA Group Operation and Maintenance, North Mosaddeq St., Mirdamad Blvd., Tehran, Iran
AUTHOR
[1] M.W. Bondi, E.C. Edmonds and D.P. Salmon, Alzheimer’s Disease: Past, Present, and Future, J. Int. Neuropsychol. Soc.23 (2017) 818-831.
1
[2] R.U. Haque and A.I. Levey, Alzheimer’s disease: A clinical perspective and future nonhuman primate research opportunities, PNAS 116 (2019) 26224-26229.
2
[3] D.J. Selkoe, Alzheimer ’s disease: genes, proteins and therapy, Physiol. Rev. 81 (2001) 741–766.
3
[4] J. Park, J. Seo , J. Won , H. Yeo and Y. Ahn, Abnormal Mitochondria in a Non-human Primate Model of MPTP-induced Parkinson’s Disease: Drp1 and CDK5/p25 Signaling. Exp Neurobiol 28 (2019) 414–424.
4
[5] K. Pozo and J.A. Bibb, The Emerging Role of Cdk5 in Cancer. Trends Cancer 10 (2016) 606–618.
5
[6] J. Seo, O. Kritskiy, L.A. Watson, S.J. Barker, D. Dey, W.K. Raja, Y.T. Lin, T. Ko, S. Cho, J. Penney, M.C. Silva, S.D. Sheridan, D. Lucente and J.F. Gusella, Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia. J. Neurosci. 37 (2017) 9917–9924.
6
[7] Y.L. Zheng, N.D. Amin, Y.F. Hu, P. Rudrabhatla, V. Shukla, J. Kanungo, S. Kesavapany, P. Grant, W. Albers and H.C. Pant, A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation. J. Biol. Chem. 285 (2010) 34202–34212.
7
[8] M. Kolarova, F. García-Sierra, A. Bartos, J. Ricny and D. Ripova, Structure and pathology of tau protein in Alzheimer disease, Int. J. Alzheimers Dis. 2012 (2012) 731526.
8
[9] J. Herzog, S.M. Ehrlich, L. Pfitzer, J. Liebl, T. Frohlich, G.J. Arnold, W. Mikulits, C. Haider, A.M. Vollmar and S. Zahler, Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1alpha: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma. Oncotarget. 7 (2016) 27108-27121.
9
[10] J.H. Christopher, A.S. Mark and B.C. Christopher, Discovery and SAR of 2-ami-nothiazole inhibitors of CDK5/p25 as a potential treatment for Alzheimer’s disease, Bioorg. Med. Chem. Lett. 14 (2004) 5521-5525.
10
[11] M. Tadayon and Z. Garkani-Nejad, In silico study combining QSAR, docking and molecular dynamics simulation on 2,4- disubstituted pyridopyrimidine derivatives, J. Recept. Signal Trans. 39:2 (2019) 167-174.
11
[12] H. Safarizadeh and Z. Garkani-Nejad, Molecular docking, molecular dynamics simulations and QSAR studies on some of 2-arylethenylquinoline derivatives for inhibition of Alzheimer's amyloid-beta aggregation: Insight into mechanism of interactions and parameters for design of new inhibitors, J. Mol. Graph. Model. 87 (2019) 129-143.
12
[13] M. Shiradkar, J. Thomas, V. Kanase and R. Dighe, Studying Synergism of Methyl Linked Cyclohexyl Thiophenes with Triazole: Synthesis and Their Cdk5/P25 Inhibition Activity, Eur. J. Med. Chem. 46 (2011)2066-2074.
13
[14] SYBYL package, Tripos Inc.: St. Louis, MO, USA, (2006), Available online: http://www.tripos.com.
14
[15] D.M. Chhatbar, U.J. Chaube, V.K. Vyas and H.G. Bhatt, CoMFA, CoMSIA, Topomer CoMFA, HQSAR, molecular docking and molecular dynamics simulations study of triazine morpholino derivatives as mTOR inhibitors for the treatment of breast cancer, Comp. Bio. Chem. 80 (2019) 351–363.
15
[16] A. Khaldan, K.E. khatabi, R. El-Mernissi, A. Ghaleb, R. Hmamouchi, A. Sbai, M. Bouachrine and T. Lakhlifi, 3D-QSAR Modeling and Molecular Docking Studies of novel triazoles-quinine derivatives as antimalarial agents, J. Mater. Environ. Sci. 11 (2020) 429-443.
16
[17] J. Sun, S. Cai, N. Yan and H. Mei, Docking and 3D-QSAR studies of influenza neuraminidase inhibitors using three-dimensional holographic vector of atomic interaction field analysis, Eur. J. Med. Chem. 45 (2010) 1008–1014.
17
[18] J. Zhu, Q. Yu, Y. Cai, Y. Chen, H. Liu, W. Liang and J. Jin, Theoretical Exploring Selective-Binding Mechanisms of JAK3 by 3D-QSAR, Molecular Dynamics Simulation and Free Energy Calculation. Front. Mol. Biosci. 7 (2020) 1-12.
18
[19] Z.Q. Yang and P.H. Sun, 3D-QSAR Study of Potent Inhibitors of Phosphodiesterase-4 Using a CoMFA Approach, Int. J. Mol. Sci. 8 (2007)714–722.
19
[20] Q.L. Song, P.H. Sun and W.M. Chen, Exploring 3D-QSAR for Ketolide Derivatives as Antibacterial Agents Using CoMFA and CoMSIA, Lett. Drug Des. Discov. 7 (2010) 149–159.
20
ORIGINAL_ARTICLE
Application of Polyethylene Glycol Grafted-CuO Nanoparticles in Solid Phase Extraction of Phthalate Esters in Baby Shampoo and Body Wash
This study considers identification and determination of phthalates esters in cosmetic samples. The dispersive solid phase extraction was used for extraction of analytes prior to high performance liquid chromatography analysis. The solid sorbent for extraction was polyethylene glycol grafted on cupric oxide nanoparticles (PEG-g-CuO-NPs). This sorbent was first synthesized and characterized by scanning electron microscopy (SEM), Energy-dispersive X-ray(EDX) and fourier-transform infrared spectroscopy (FT-IR) then efficiently applied for extraction of analytes. The extraction conditions like amount of sorbent, kind and volume of desorption solvent, extraction and desorption time, and pH of sample solution were optimized. The validation of method carried out under optimum conditions. Linear ranges were 0.005-4 µgmL-1 with the coefficient correlation (R2) in the range of 0.9914-0.9962. The limits of detection (LODs) (3S/N) were 0.0025 to 0.005 µgmL-1 and acceptable repeatability’s (RSDs below 6.45%, n=5) obtained. Application of proposed method was investigated by extraction of phthalates in shampoo and body wash for babies which satisfaction results achieved.
https://ijac.journals.pnu.ac.ir/article_7789_4d8fbdffed1b8dd277f724049c4f0440.pdf
2021-03-01
39
49
10.30473/ijac.2021.59367.1190
phthalate esters
HPLC
Baby shampoo
Body wash
polyethylene glycol grafted cupric oxide nano particles
Nourolhoda
Razavi
razavihoda@yahoo.com
1
Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad. Mashhad, Iran
AUTHOR
Amene
Zendegi-Shiraz
amenezendegi@gmail.com
2
Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad. Mashhad, Iran
AUTHOR
Zarrin
Eshaghi
eshaghi@pnu.ac.ir
3
Department of Chemistry, Payame Noor University, 19395-4697 Tehran, Iran
LEAD_AUTHOR
[1] P.Gimeno, A.F. Maggio, C. Bousquet, A. Quoirez, C. Civade and P.A. Bonnet, Analytical method for the identification and assay of 12 phthalates in cosmetic products: Application of the ISO 12787 international standard “Cosmetics–Analytical methods–Validation criteria for analytical results using chromatographic techniques”, J. Chromatogr. A. 1253 (2012) 144-53.
1
[2] J.C. Hubinger and D.C. Havery, Analysis of consumer cosmetic products for phthalate esters. J.Cosmet. Sci. 57 (2) (2006) 127-37.
2
[3] A. Manayi, M. Kurepaz-mahmoodabadi, A.R. Gohari, Y. Ajani and S. Saeidnia, Presence of phthalate derivatives in the essential oils of a medicinal plant Achillea tenuifolia, DARU J. Pharm. Sci. 22 (2014) 1-6.
3
[4] X. Lv, Y. Hao and Q. Jia, Preconcentration procedures for phthalate esters combined with chromatographic analysis. J. Chromatogr. Sci. 51 (2013) 632-44.
4
[5] K.E. Kelley, S. Hernández-Díaz, E.L. Chaplin, R. Hauser, A.A. Mitchell, Identification of phthalates in medications and dietary supplement formulations in the United States and Canada. Environ. Health Perspect. 120 (3) (2012) 110-116 .
5
[6] H.Chen, C. Wang,X. Wang, N.Hao and J. Liu, Determination of phthalate esters in cosmetics by gas chromatography with flame ionization detection and mass spectrometric detection. Int. J. Cosmet. Sci. 27 (4) (2005) 205-10 .
6
[7] D. Koniecki, R. Wang, P.R. Moody and J. Zhu, Phthalates in cosmetic and personal care products: concentrations and possible dermal exposure. Environ. Res. 111(3) (2011) 329-36.
7
[8] G. Navaranjan, T.K. Takaro, A.J. Wheeler, M.L. Diamond, H. Shu, M.B. Azad, A.B. Becker, R. Dai, S.A. Harris, D.L. Lefebvre, Z. Lu, P.J. Mandhane, K. McLean, T.J. Moraes, J.A. Scott, S.E. Turvey, M.R. Sears, P. Subbarao and J.R. Brook, J. Expo. Sci. Environ. Epidemiol. 30 (2020) 70–85.
8
[9] S.H. Kim, M.J. Park, Phthalate exposure and childhood obesity. J. Pediatr. Endocrinol. Metab. 19 (2) (2014) 69-75.
9
[10] B. Prasad, Phthalate pollution: environmental fate and cumulative human exposure index using the multivariate analysis approach, Environ. Sci.: Process. Impacts 23 (2021) 389-399.
10
[11] J. Apau, W. Sefah and E. Adua, Human contact with phthalates during early lifestages leads to weight gain and obesity, Cogent Chem. 6 (2020) 688-701.
11
[12] L. Lucaccioni , V. Trevisani, E. Passini, B. Righi, C. Plessi, B. Predieri and L. Iughetti, Perinatal exposure to phthalates: from endocrine to neurodevelopment effects, Int. J. Mol. Sci. 22 (2021) 4063.
12
[13] I. Lee, J.Y. Park, S.Kim, J. Nam –An, J. Lee, H. Park, S. K. Jung, S.Y. Kim, J. P. Lee and K. Choi, Association of exposure to phthalates and environmental phenolics with markers of kidney function: Korean National Environmental Health Survey (KoNEHS) 2015-2017, Environ. Int.143(2020)105877.
13
[14] A. Moeller, K.H. Carlsen, P.D. Sly, E. Baraldi,G. Piacentini, I.Pavord, C. Lex and S. Saglani, Monitoring asthma in childhood: lung function, bronchial responsiveness and inflammation, Eur. Respir. Rev. 24 (2015) 204–215.
14
[15] M. Mariana, J. Feiteiro, I. Verde, E. Cairrao, The effects of phthalates in the cardiovascular and reproductive systems: A review. Environ. Int. 9492016)758-776.
15
[16] P.R. Hannon and J.A. Flaws, The effects of phthalates on the ovary. Front. Endocrinol. 6 (2015) 8-11.
16
[17] K.A. Baken, N. Lambrechts, S. Remy, V. Mustieles, A. Rodríguez-Carrillo, C.M. Neophytou, N. Olea and G. Schoeters, A strategy to validate a selection of human effect biomarkers using adverse outcome pathways: Proof of concept for phthalates and reproductive effects, 175 (2019) 235-256.
17
[18] H.Y. Shen, H.L. Jiang, H.L.Mao, G. Pan, L. Zhou and Y.F. Cao, Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC‐DAD and GC‐MS methods. J. Sep. Sci. 30 (1) (2007) 48-54.
18
[19] L. Liu, Z. Wang, S. Zhao, J. Duan, H. Tao and W. Wang, et al. Determination of total phthalate in cosmetics using a simple three-phase sample preparation method. Anal. Bioanal. Chem. 410 (4) (2018) 1323-1331.
19
[20] J.Qiao, M. Wang, H. Yan and G. Yang, Dispersive solid-phase extraction based on magnetic dummy molecularly imprinted microspheres for selective screening of phthalates in plastic bottled beverages. J. Agric. Food Chem.62 (13) (2014) 2782-2789.
20
[21] Y.Cai, Y.E. Cai, Y. Shi, J. Liu, S. Mou and Y. Lu, A liquid–liquid extraction technique for phthalate esters with water-soluble organic solvents by adding inorganic salts. Microchim.Acta 157 (1-2) (2007) 73-79.
21
[22] Y.Fan, H. Chen, H. Liu, F. Wang, S. Ma and A. Latipa, , et al. Analysis of phthalate esters in dairy products—a brief review. Anal. Methods 9 (3) (2017) 370-380.
22
[23] A. Andrade-Eiroa, M. Canle and V. Leroy-Cancellieri, V. Cerdà, Solid-phase extraction of organic compounds: a critical review. Part II. TrAC Trends Anal. Chem. 80 (2016) 655-67.
23
[24] J. González-Sálamo, B. Socas-Rodríguez and J. Hernández-Borges, Analytical methods for the determination of phthalates in food. Curr. Opin. Food Sci. 22 (2018) 122-136.
24
[25] J.G. Wu, Determination of eleven phthalate esters using HPLC and UV diode‐array detector with liquid‐liquid extraction or on line preconcentration. J.Environ. Sci.Health Part A. 26 (8) (1991) 1363-1385.
25
[26] N. Razavi and A. Sarafraz Yazdi, New application of chitosan‐grafted polyaniline in dispersive solid‐phase extraction for the separation and determination of phthalate esters in milk using high‐performance liquid chromatography. J. Sep. Sci. 40 (8) (2017) 1739-1746 .
26
[27] A. Kiani, M. Ahmadloo, N. Shariatifar, M. Moazzen, A.N. Baghani and G.J. Khaniki, et al. Method development for determination of migrated phthalate acid esters from polyethylene terephthalate (PET) packaging into traditional Iranian drinking beverage (Doogh) samples: a novel approach of MSPE-GC/MS technique. Environ. Sci. Pollut. Res. Int. 25 (13) (2018) 2728-12738.
27
[28] S.H. Jeon, Y.P. Kim, Y. Kho, J.H. Shin, W.H. Ji and Y.G. Ahn, Development and Validation of Gas Chromatography-Triple Quadrupole Mass Spectrometric Method for Quantitative Determination of Regulated Plasticizers in Medical Infusion Sets. J. Anal. Methods Chem.(2018).
28
[29] A. Zendegi-Shiraz, Z. Es’haghi and M. Hassanzadeh-Khayyat, Synthesis and characterization of composite polymer, polyethylene glycol grafted flower-like cupric nano oxide for solid phase microextraction of ultra-trace levels of benzene, toluene, ethyl benzene and o-xylene in human hair and water samples. J. Chromatogr. A. 1418 (2015) 21-28.
29
[30] J. Feng, M. Sun, Y. Bu and C. Luo, Nanostructured copper‐coated solid‐phase microextraction fiber for gas chromatographic analysis of dibutyl phthalate and diethylhexyl phthalate environmental estrogens. J. Sep. Sci. 38 (1) (2015) 128-33.
30
[31] N.Adhoum and L. Monser, Removal of phthalate on modified activated carbon: application to the treatment of industrial wastewater. Sep. Purif. Technol. 38 (3) (2004) 233-239.
31
[32] S.Zheng, X. Li, X., Y.Zhang, Q. Xie, Y.S. Wong and W. Zheng, et al. PEG-nanolized ultrasmall selenium nanoparticles overcome drug resistance in hepatocellular carcinoma HepG2 cells through induction of mitochondria dysfunction. Int. J. Nanomedicine 7 (2012) 3939-49.
32
[33] H. Siddiqui, M. Qureshi and F.Z. Haque, Surfactant assisted wet chemical synthesis of copper oxide (CuO) nanostructures and their spectroscopic analysis. Optik 127 (5) (2016) 2740-2747.
33
[34] S.Taghavi Fardood and A. Ramazani, Green synthesis and characterization of copper oxide nanoparticles using coffee powder extract. J. Nanostructures. 6 (2) (2016) 167-71.
34
[35] J.C.Hubinger and D.C. Havery, Analysis of consumer cosmetic products for phthalate esters J. Cosmet. Sci. 57 (2003) 127-137.
35
[36] S. Cavar Zeljkovic, S. Becirovic, A. Goga and M.Kezic, Influence of Solvent and Extraction Type on Phthalate Determination in Cosmetic Products. Anal. Chem.Lett. 4 (2014) 313-318.
36
[37] H. Chen, C. Wang , X. Wang , N. Hao and J. Liu, Determination of phthalate esters in cosmetics by gas chromatography with flame ionization detection and mass spectrometric detection. Int. J. Cosmet. Sci. 27 (2005) 205-210.
37
[38] D.Koniecki, R.Wang, R.P. Moody and J. Zhu, Phthalates in cosmetic and personal care products: concentrations and possible dermal exposure, Environ. Res. 111 (2011) 329-336.
38
[39] J.C. Hubinger, A survey of phthalate esters in consumer cosmetic products. J. Cosmet. Sci. 61(2010)457-465.
39
[40] H. Guo, N. Song, D. Wang, J. Ma and Q. Jia, A modulation approach for covalent organic frameworks: Application to solid phase microextraction of phthalate esters. Talanta 198 (2019) 277-283.
40
[41] Z. Mehrani, H. Ebrahimzadeh, E. Moradi, Poly m-aminophenol/nylon 6/graphene oxide electrospun nanofiber as an efficient sorbent for thin film microextraction of phthalate esters in water and milk solutions preserved in baby bottle. J. Chromatogr. A 1600 (2019) 87-94.
41
[42] Y. Tong, X. Liu and L. Zhang, Green construction of Fe3O4@ GC submicrocubes for highly sensitive magnetic dispersive solid-phase extraction of five phthalate esters in beverages and plastic bottles. Food Chem. 277 (2019) 579-585.
42
ORIGINAL_ARTICLE
Molecular Docking and Molecular Dynamics Studies of Ectoine Drug and Polyamidoamine/Ectoine Conjugates With the 6twk Protein
The interactions of 6twk protein with Ectoine drug, Polyamidoamine (PAMAM) /Ectoine and histidine modified PAMAM/Ectoine were investigated using molecular docking and molecular dynamics simulation. Based on the results of molecular docking increasing of binding energy and the decreasing of inhibition constant of the compounds, increase their inhibitory activity. Protein stability in complex with these ligands was investigated using molecular dynamics simulation approach. Results molecular dynamics simulation displayed that histidine modified PAMAM/Ectoine with the lowest mean square displacement (MSD) is the better suitable to deliver the ectoine drug. This causes the most controlled/diffusion of ectoine drug molecule. So, histidine modified PAMAM/Ectoine conjugate can be introduced for further investigations on interaction of ectoine drug and 6twk protein.
https://ijac.journals.pnu.ac.ir/article_7793_d6b95c062d3be2b24ef56a194894553e.pdf
2021-03-01
50
55
10.30473/ijac.2021.59403.1193
molecular docking
Inhibitory activity
Molecular Dynamics
PAMAM/Ectoine Conjugate
Nosrat
Madadi Mahani
nmmadady@gmail.com
1
Department of Chemistry, Payame Noor University, 19395-4697 Tehran, Iran
LEAD_AUTHOR
[1] L. Nair, S. Jagadeeshan, S.A. Nair and G.V. Kumar, Biological evaluation of 5-fluorouracil nanoparticles for cancer chemotherapy and its dependence on the carrier PLGA, Int. J. Nanomedicine 6 (2011) 1685-1697.
1
[2] A. Rengaraj, P. Puthiaraj, Y. Haldorai, N.S. Heo, S.K. Hwang, Y.K. Han, S. Kwon, W.S. Ahn and Y.S. Huh, Porous Covalent Triazine Polymer as a Potential Nanocargo for Cancer Therapy and Imaging, ACS Appl. Mater. Interfaces 8 (2016) 8947–8955.
2
[3] K. Ariga, K. Kawakami, M. Ebara, Y. Kotsuchibashi, Q. Ji and J.P. Hill, Bioinspired nanoarchitectonics as emerging drug delivery systems, New J. Chem. 38 (2014) 5149–5163.
3
[4] U. Boas and P.M. Heegaard, Dendrimers in drug research, Chem. Soc. Rev. 33 (2004) 43–63.
4
[5] C. Dufes, I.F. Uchegbu and A.G. Schatzlein, Dendrimers in gene delivery, Adv. Drug Delivery Rev. 57 (2005) 2177–2202.
5
[6] Y. Cheng, Z. Xu, M. Ma and T. Xu, Dendrimers as drug carriers: applications in different routes of drug administration, J. Pharm. Sci. 97 (2008) 123–143.
6
[7] S. Sadekar and H. Ghandehari, Transepithelial transport and toxicity of PAMAM dendrimers: implications for oral drug delivery, Adv. Drug Delivery Rev. 64 (2012) 571–588.
7
[8] C. Pan, C. Kumar, S. Bohl, U. Klingmueller and M. Mann, Comparative proteomic phenotyping of cell lines and primary cells to assess preservation of cell type-specific functions, Mol. Cell. Proteomics 8 (2009) 443–450.
8
[9] X. Zhang, Y. Zeng, T. Yu, J. Chen, G. Yang and Y. Li, Tetrathiafulvalene terminal-decorated PAMAM dendrimers for triggered release synergistically stimulated by redox and CB, Langmuir 30 (2014) 718–726.
9
[10] F. Aulenta, W. Hayes and S. Rannard, Dendrimers: a new class of nanoscopic containers and delivery devices, Eur. Pol. J. 39 (2003) 1741-1771.
10
[11] S.Y. Wu, H.Y. Chou, H.C. Tsai, R. Anbazhagan, C.H. Yuh, J. M.Yang and Y.H. Chang, Amino acid-modified PAMAM dendritic nanocarriers as effective chemotherapeutic d rug vehicles in cancer treatment: a study using zebrafish as a cancer model, RSC Adv. 10 (2020) 20682- 20690.
11
[12] M. Sheikhpour, A. Sadeghi, F. Yazdian, A. Movafagh and A. Mansoori, Anticancer and apoptotic effects of ectoine and hydroxyectoine on non-small cell lung cancer cells: An in-vitro investigation, Multidiscipl. Cancer Invest. 3 (2019) 14-20.
12
[13] J.M. Pastor, M. Salvador, M. Argandona, V. Bernal, M. Reina-Bueno, L.N. Csonka, J.L. Iborra, C. Vargas, J.J. Nieto and M. Canovas, Ectoines in cell stress protection: Uses and biotechnological production, Biotechnol. Adv. 28 (2010) 782–801.
13
[14] M.B. Hahn, S. Meyer, M.A. Schroter, H. J. Kunte,T. Solomun and H. Sturm, DNA protection by ectoine from ionizing radiation Molecular mechanisms. Phys. Chem. Chem. Phys. 19 (2017) 25717–25722.
14
[15] R. Dias and W. Filgueira de Azevedo Jr, Molecular docking algorithms, Curr. Drug Targets 9 (2008) 1040-1047.
15
[16] A. Rengaraj, B. Subbiah, Y. Haldorai, D. Yesudhas, H.J. Yun, S. Kwon, S. Choi, Y.K. Han, E.S. Kim, H. Shenpagam and Y.S. Huh, PAMAM/5-fluorouracil drug conjugate for targeting E6 and E7 oncoproteins in cervical cancer: a combined experimental/in silico approach, RSC Adv. 7(2017) 5046-5054.
16
[17] Z. Shariatinia, A. Mazloom Jalali and F. Afshar Taromi, Molecular dynamics simulations on desulfurization of n-octane/thiophene mixture using silica filled polydimethylsiloxane nanocomposite membranes, 24 (2016) Model Simul. Mater. Sci. Eng. 035002- 035011.
17
[18] A. Mazloom Jalali, Z. Shariatinia and F. Afshar Taromi, Desulfurization efficiency of polydimethylsiloxane/silica nanoparticle nanocomposite membranes: MD simulations, Comput. Mater Sci. 139 (2017) 115–124.
18
[19] S. Salar, F. Mehrnejad, R.H. Sajedi and J. Mohammadnejad Arough, Chitosan nanoparticles-trypsin interactions: biophysicochemical and molecular dynamics simulation studies, Int. J. Biol. Macromol. 103 (2017) 902–909.
19
[20] M. Yahyaei, F. Mehrnejad, H. Naderi-manesh and A.H. Rezayan, Follicle-stimulating hormone encapsulation in the cholesterolmodified chitosan nanoparticles via molecular dynamics simulations and binding free energy calculations, Eur. J. Pharm. Sci. 107(2017) 126–137.
20
[21] G. Morris and R. Huey, AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility, J. Comput. Chem. 30(2009) 2785-2791.
21
[22] H. Sun, COMPASS: an ab initio force-field optimized for condensed-phase applications overview with details on alkane and benzene compounds, J. Phys. Chem. B 102(1998) 7338–7364.
22
[23] D.P. Otto and M.M. de Villiers, All-atomistic molecular dynamics (AA-MD) studies and pharmacokinetic performance of PAMAM-dendrimer-furosemide delivery systems, Int. J. Pharm. 547(2018) 545–555.
23
[24] X.D. Guo, J.P.K. Tan, S.H. Kim, L.J. Zhang, Y. Zhang, J.L. Hedrick, Y.Y. Yang and Y. Qian, Computational studies on self-assembled paclitaxel structures: templates for hierarchical block copolymer assemblies and sustained drug release, Biomaterials 30 (2009) 6556–6563.
24
[25] M.M. Mirhosseini, M. Rahmati, S.S. Zargarian and R. Khordad, Molecular dynamics simulation of functionalized graphene surface for high efficient loading of doxorubicin, J. Mol. Struct. 1141(2017) 441–450.
25
[26] Accelrys Software Inc., San Diego, (2017).
26
[27] K. Sargsyan, C. Grauffel and C. Lim, How molecular size impacts RMSD applications in molecular dynamics simulations, J. Chem. Theory Comput. 13(2017) 1518−1524.
27
[28] Y. Liu, V.S. Bryantsev and M.S. Diallo, et al., PAMAM dendrimers undergo pH responsive conformational changes without swelling, J. Am. Chem. Soc. 131 (2009) 2798–2799.
28
ORIGINAL_ARTICLE
Anion-Doped Overoxidized Polypyrrole/Multiwalled Carbon Nanotubes Modified Glassy Carbon Electrode as a New Electrochemical Sensing Platform For Buprenorphine Opioid Drug
A novel Buprenorphine (BPR) sensor is fabricated based on nanocomposite film of benzene-1,3-disulfonate anion doped overoxidized polypyrrole/multiwalled carbon modified glassy carbon electrode. The carbon nanotubes were drop-casted on bare electrode, and then thin layer of benzene-1,3-disulfonate-doped overoxidized polypyrrole formed electrochemically on it. Effect of experimental conditions involving supporting electrolyte pH, carbon nanotubes suspension drop size, and the number of potential cycles in overoxidized polymerization were optimized by monitoring the voltammetry responses of the modified electrode. Then the optimized modified electrode was used for electrochemical sensing of BPR by differential pulse voltammetry, which exhibited a linear growth with high sensitivity in anodic peak currents at the BPR concentration range of 0.06-40 µM, and a detection limit of 28 nM. Finally, the determination of BPR in urine real samples was performed by the new sensor and satisfactory results obtained.
https://ijac.journals.pnu.ac.ir/article_7794_a8f3ebc5d740d1503d78318e7f321298.pdf
2021-03-01
56
64
10.30473/ijac.2021.59410.1194
Buprenorphine
Multiwalled carbon nanotubes
Overoxidized polypyrrole
Nanocomposite
electrochemical sensor
Differential pulse voltammetry
Abdolhamid
Hatefi-Mehrjerdi
hhatefy@yahoo.com
1
Department of Chemistry, Payame Noor University (PNU), P.O. Box 19395-4697, Tehran, Iran
LEAD_AUTHOR
ُُSoghra
Rafiei Boldaji
rafiei.soghra@znu.ac.ir
2
Department of Chemistry, Payame Noor University (PNU), P.O. Box 19395-4697, Tehran, Iran
AUTHOR
Mohammad Reza
Yaftian
yaftian@znu.ac.ir
3
Department of Chemistry, Faculty of Science, University of Zanjan, P.O. Box 45371-38791, Zanjan, Iran
AUTHOR
Hassan
Shayani-Jam
shayan@znu.ac.ir
4
Department of Chemistry, Faculty of Science, University of Zanjan, P.O. Box 45371-38791, Zanjan, Iran
AUTHOR
[1] J.M.P.J. Garrido, M.P.M. Marques, A.M.S. Silva, T.R.A. MacEdo, A.M.Oliveira-Brett and F. Borges, Spectroscopic and electrochemical studies of cocaine-opioid interactions, Anal. Bioanal. Chem., 388 (2007) 1799–1808.
1
[2] R.E. Johnson, P.J. Fudala and R. Payne, Buprenorphine: Considerations for pain management, J. Pain Symptom Manage., 29 (2005) 297–326.
2
[3] B. Holmes and R.C. Heel, Flecainide A review of its pharmacological properties and therapeutic efficacy, Curr. Ther. (Seaforth)., 26 (1985) 17–23.
3
[4] W. Huang, D.E. Moody and E.F. McCance-Katz, The in vivo glucuronidation of buprenorphine and norbuprenorphine determined by liquid chromatography-electrospray ionization-tandem mass spectrometry, Ther. Drug Monit., 28 (2006) 245–251.
4
[5] S. Pirnay, F. Hervé, S. Bouchonnet, B. Perrin, F.J. Baud and I. Ricordel, Liquid chromatographic-electrospray ionization mass spectrometric quantitative analysis of buprenorphine, norbuprenorphine, nordiazepam and oxazepam in rat plasma, J. Pharm. Biomed. Anal., 41 (2006) 1135–1145.
5
[6] J. Mendelson, R.A. Upton, E.T. Everhart, P. Jacob and R.T. Jones, Bioavailability of sublingual buprenorphine, J. Clin. Pharmacol., 37 (1997) 31–37.
6
[7] M. Ohtani, H. Kotaki, K. Uchino, Y. Sawada and T. Iga, Pharmacokinetic analysis of enterohepatic circulation of buprenorphine and its active metabolite, norbuprenorphine, in rats, Drug Metab. Dispos., 22 (1994) 2–7.
7
[8] I.I. Papoutsis, P.D. Nikolaou, S.A. Athanaselis, C.M. Pistos, C.A. Spiliopoulou and C.P. Maravelias, Development and validation of a highly sensitive GC/MS method for the determination of buprenorphine and nor-buprenorphine in blood, J. Pharm. Biomed. Anal., 54 (2011) 588–591.
8
[9] D.E. Moody, J.D. Laycock, A.C. Spanbauer, D.J. Crouch, R.L. Foltz, J.L. Josephs, L. Amass and W.K. Bickel, Determination of buprenorphine in human plasma by gas chromatography- positive ion chemical ionization mass spectrometry and liquid chromatography- tandem mass spectrometry, J. Anal. Toxicol., 21 (1997) 406–414.
9
[10] F. Lagrange, F. Pehourcq, M. Baumevieille and B. Begaud, Determination of buprenorphine in plasma by liquid chromatography: Appication to heroin-dependent subjects, J. Pharm. Biomed. Anal., 16 (1998) 1295–1300.
10
[11] L. Mercolini, R. Mandrioli, M. Conti, C. Leonardi, G. Gerra, and M.A. Raggi, Simultaneous determination of methadone, buprenorphine and norbuprenorphine in biological fluids for therapeutic drug monitoring purposes, J. Chromatogr. B Anal. Technol. Biomed. Life Sci., 847 (2007) 95–102.
11
[12] W.J. Liaw, S.T. Ho, J.J. Wang, O.Y.P. Hu and J.H. Li, Determination of morphine by high-performance liquid chromatography with electrochemical detection: Application to human and rabbit pharmacokinetic studies, J. Chromatogr. B Biomed. Appl., 714 (1998) 237–245.
12
[13] A. Tracqui, P. Kintz and P. Mangin, HPLC/MS Determination of Buprenorphine and Norbuprenorphine in Biological Fluids and Hair Samples, J. Forensic Sci., 42 (1997) 14077J.
13
[14] F. Lopes, J.G. Pacheco, P. Rebelo and C. Delerue-Matos, Molecularly imprinted electrochemical sensor prepared on a screen printed carbon electrode for naloxone detection, Sensors Actuators, B Chem., 243 (2017) 745–752.
14
[15] J. Sochor, J. Dobes, O. Krystofova, B. Ruttkay-Nedecky, P. Babula, M. Pohanka, T. Jurikova, O. Zitka, V. Adam, B. Klejdus and R. Kizek, Electrochemistry as a tool for studying antioxidant properties, Int. J. Electrochem. Sci., 8 (2013) 8464–8489.
15
[16] M.A. García-Fernández, M.T. Fernández-Abedul and A. Costa-García, Voltammetric study and determination of buprenorphine in pharmaceuticals, J. Pharm. Biomed. Anal., 21 (1999) 809–815.
16
[17] A.R. Fakhari, A. Sahragard and H. Ahmar, Development of an Electrochemical Sensor Based on Reduced Graphene Oxide Modified Screen-Printed Carbon Electrode for the Determination of Buprenorphine, Electroanalysis, 26 (2014) 2474–2483.
17
[18] M. Behpour, A. Valipour and M. Keshavarz, Determination of buprenorphine by differential pulse voltammetry on carbon paste electrode using SDS as an enhancement factor, Mater. Sci. Eng. C, 42 (2014) 500–505.
18
[19] Y.C. Tsai, S.C. Li and S.W. Liao, Electrodeposition of polypyrrole-multiwalled carbon nanotube-glucose oxidase nanobiocomposite film for the detection of glucose, Biosens. Bioelectron., 22 (2006) 495–500.
19
[20] X. Dang, H. Hu, S. Wang and S. Hu, Nanomaterials-based electrochemical sensors for nitric oxide, Microchim. Acta, 182 (2014) 455–467.
20
[21] I.S. Chronakis, S. Grapenson and A. Jakob, Conductive polypyrrole nanofibers via electrospinning: Electrical and morphological properties, Polymer (Guildf)., 47 (2006) 1597–1603.
21
[22] H. Peng, L. Zhang, C. Soeller and J. Travas-Sejdic, Conducting polymers for electrochemical DNA sensing, Biomaterials, 30 (2009) 2132–2148.
22
[23] M. Ates, A review study of (bio)sensor systems based on conducting polymers, Mater. Sci. Eng. C, 33 (2013) 1853–1859.
23
[24] R.K. Shervedani, A.Z. Isfahani, R. Khodavisy and A. Hatefi-Mehrjardi, Electrochemical investigation of the anodic corrosion of Pb-Ca-Sn-Li grid alloy in H2SO4 solution, J. Power Sources, 164 (2007) 890–895.
24
[25] A. Hassanein, N. Salahuddin, A. Matsuda, G. Kawamura and M. Elfiky, Fabrication of biosensor based on Chitosan-ZnO/Polypyrrole nanocomposite modified carbon paste electrode for electroanalytical application, Mater. Sci. Eng. C, 80 (2017) 494–501.
25
[26] Y.S. Gao, J.K. Xu, L.M. Lu, L.P. Wu, K.X. Zhang, T. Nie, X.F. Zhu and Y. Wu, Overoxidized polypyrrole/graphene nanocomposite with good electrochemical performance as novel electrode material for the detection of adenine and guanine, Biosens. Bioelectron., 62 (2014) 261–267.
26
[27] S. Shahrokhian, M. Azimzadeh and P. Hosseini, Modification of a glassy carbon electrode with a bilayer of multiwalled carbon nanotube/benzene disulfonate-doped polypyrrole: Application to sensitive voltammetric determination of olanzapine, RSC Adv., 4 (2014) 40553–40560.
27
[28] S. Shahrokhian and M. Ghalkhani, Glassy carbon electrodes modified with a film of nanodiamond-graphite/chitosan: Application to the highly sensitive electrochemical determination of Azathioprine, Electrochim. Acta, 55 (2010) 3621–3627.
28
[29] E. Laviron, General expression of the linear potential sweep voltammogram in the case of diffusionless electrochemical systems, J. Electroanal. Chem., 101 (1979) 19–28.
29
[30] A. Farmany, M. Shamsara and H. Mahdavi, Enhanced electrochemical biosensing of Buprenorphine opioid drug by highly stabilized magnetic nanocrystals, Sensors Actuators, B Chem., 239 (2017) 279–285.
30
ORIGINAL_ARTICLE
A Novel Optode for Vanadium Speciation: Sol–Gel Based Optical Sensor for Vanadium Determination
A highly selective optical sensor for V(IV) ions was established depended on entrapment of a sensitive reagent, 5-(2`,4`-dimethylphenylazo)-6-hydroxy-pyrimidine-2,4-dione (DMPAHPD), in a silica sol–gel thin film coated on a glass substrate. The thin films fabricated depended on tetraethoxysilane (TEOS) as precursor, sol–gel of pH = 2.5, water: alkoxyde ratio of 4: 1 and DMPAHPD concentration of 2.5 × 10−4 M. The effect of sol–gel parameters on sensing behavior of the fabricated sensor was also illustrated. The fabricated sensor can be used to detect V(IV) ion with an outstanding high selectivity over a wider dynamic range of 5.0–145 ng mL−1 and a detection limit of 1.35 ng mL−1. It also recorded reproducible results with relative standard deviation of 1.75% and 1.02% for 20 and 70 ng mL−1 of V(IV), respectively, along with a fast response time of two min. Total vanadium was determined after reduction of V(V) to V(IV) using ascorbic acid as reducing agent. The V(V) amounts were estimated by subtracting the concentration of V(IV) from the total vanadium concentration. Interference studies reported a good selectivity for V(IV) with trapping DMPAHPD into sol–gel matrix and appropriately adjusting the structure of doped sol–gel. The proposed sensor was compared with others and was applied to define vanadium in different environmental samples with good results.
https://ijac.journals.pnu.ac.ir/article_7799_65a9aa1462b8001c56ee675612ab2542.pdf
2021-03-01
65
77
10.30473/ijac.2021.58282.1183
Optical Sensor Membrane
Vanadium Determination
Spectrophotometry
Environmental Analysis
Alaa
Amin
asamin2005@hotmail.com
1
Chemistry Department, Faculty of Science, Benha University, Benha, Egypt
LEAD_AUTHOR
Hesham
El-Feky
heshamelfeky2010@yahoo.com
2
Chemistry Department, Faculty of Science, Benha University, Benha, Egypt
AUTHOR
[1] Z. Chen, and L.G.Owens, Trends in speciation analysis of vanadium in environmental samples and biological fluids—a review, Anal. Chim. Acta 607 (2008) 1–14.
1
[2] A.L. Rosen, and G.M. Hieftje, Inductively coupled plasma mass spectrometry and electrospray mass spectrometry for speciation analysis: applications and instrumentation, Spectrochim. Acta (B) 59 (2004) 135–146.
2
[3] K.T.G. Naeemullah, and M.Tuzen, Magnetic stirrer induced dispersive ionic-liquid microextraction for the determination of vanadium in water and food samples prior to graphite furnace atomic absorption spectrometry, Food Chem. 172 (2015) 161–165.
3
[4] S.K. Wadhwa, M. Tuzen, T.G. Kazi, and M. Soylak, Graphite furnace atomic absorption spectrometric detection of vanadium in water and food samples after solid phase extraction on multiwalled carbon nanotubes, Talanta 116 (2013) 205–209.
4
[5] K.G. Fernandes, A.R.A. Nogueira, J.A.G. Neto, and J.A. Nóbrega, Determination of vanadium in urine by electrothermal atomic absorption spectrometry using hot injection and preconcentration into the graphite tube, J. Braz. Chem. Soc. 15(2004) 676–690.
5
[6] A.R. Khan, D.C. Crans, R. Pauliukaite, and E. Norkus, Spectrometric and electrochemical investigation of vanadium(V) and vanadium(IV) tartrate complexes in solution, J. Braz. Chem. Soc. 17 (2006) 895–903.
6
[7] K. Pyrzynska, and T. Wierzbicki, Determination of vanadium species in environmental samples, Talanta 64 (2004) 823–829.
7
[8] H. Tavallali, and G. Hosseini, Colorimetric “naked eye” sensing of anions in aqueous solution, Am. Lab. 25 (2002) 40–47.
8
[9] D. Wang, and S.A.S. Wilhelmy, Development of an analytical protocol for the determination of V(IV) and V(V) in seawater: Application to coastal environments, Mar. Chem. 112 (2008) 72–80.
9
[10] M.J.C. Taylor, and J.F.V. Staden, Spectrophotometric determination of vanadium(IV) and vanadium(V) in oeach ther's presence. Review, Analyst 119 (1994) 1263–1276.
10
[11] L. Friberg, G.R. Nordberg, and V.B. Vouk, Handbook on the Toxicology of Metals; Elsevier-North Holland Biomedical Press: Amsterdam, (1979).
11
[12] Committee on Biologic Effects of Atmospheric Pollutants; Medical and Biologic Effects of Environmental Pollutants, Vanadium, National Academy of Sciences: Washington, D.C., (1974).
12
[13] M.D. Waters, R.A. Goyer, M.A. Mehlma, Advances in Modern Toxicology, Toxicology of Trace Elements; Wiley: New York, (1977).
13
[14] D.J.A. Davies, B.G. Bennett, Exposure Commitment Assessments of Environmental Pollutants; University of London Monitoring Assessment and Research Centre: London, (1983).
14
[15] J. Kameník, K. Dragounova, J. Kucera, Z. Bryknar, V.A. Trepakov, V. Strunga, Determination of vanadium in titanate-based ferroelectrics by INAA with discriminating gamma-ray spectrometry, J. Radioanal. Nucl. Chem. 311 (2017) 1333–1338.
15
[16] M. Hou, and J. Na, Determination of vanadium(V) with CdTe quantum dots as fluorescent probes, Anal. Bioanal. Chem. 397 (2010) 3589–3593.
16
[17] C. Rojas-Romo, V. Arancibia, D. Moreno-daCosta, and R.A. Tapia, Highly sensitive determination of vanadium(V) by catalytic adsorptive stripping voltammetry. Substituent effect on sensitivity III, Sens. Actuators (B), 224 (2016) 772–779.
17
[18] T.S.M. Tengku Azmi, A.R.M. Yusoff, and K.J. Abdul Karim, Determination of vanadium (IV) and vanadium(V) in Benfield samples by IEC with conductivity detection, Chromatographia 72 (2010) 141–144.
18
[19] R.Q. Aucelio, A. Doyle, B.S. Pizzorno, M.L.B. Tristao, and R.C. Campos, Electrothermal atomic absorption spectrometric method for the determination of vanadium in diesel and asphaltene prepared as detergentless microemulsions, Microchem. J. 78 (2004) 21–26.
19
[20] S.L.C. Ferreira, A.S. Queiroz, M.S. Fernandes, and H.C. Dos Santos, Application of factorial designs and Doehlert matrix in optimization of experimental variables associated with the preconcentration and determination of vanadium and copper in seawater by inductively coupled plasma optical emission spectrometry, Spectrochim. Acta (B) 57 (2002) 1939–1950.
20
[21] M.A. Gab-Allah, and A.B. Shehata, Determination of iron, nickel, and vanadium in crude oil by inductively coupled plasma optical emission spectrometry following microwave-assisted wet digestion, Chem. Pap. (2021) In Press, https://doi.org/10.1007/s11696-021-01633-8.
21
[22] W. Zhang, Z. Zhuo, P. Lu, T. Sun, W. Sun, and J. Lu, Determination of vanadium, iron, and nickel in petroleum coke by laser-induced breakdown spectroscopy, Spectrochim. Acta (B) 177 (2021) 106076.
22
[23] Y. Wang, and I.D. Brindle, Ultra-trace determination of vanadium in lake sediments: a performance comparison using O2, N2O, and NH3 as reaction gases in ICP-DRC-MS, J. Anal. At. Spect. 26 (2011) 1514–1520.
23
[24] K. Pyrzyńska, Recent developments in spectrophotometric methods for determination of vanadium, Microchim. Acta 149 (2005) 159–164.
24
[25] M.M.Bordbar, H. Khajehsharifi, and A. Solhjoo, PC-ANN assisted to the determination of Vanadium (IV) ion using an optical sensor based on immobilization of Eriochorome Cyanine R on a triacetylcellulose film, Spectrochim. Acta (A) 151 (2015) 225–231.
25
[26] A.A. Mohamed, A.T. Mubarak, K.F. Fawy, and M.F. El-Shahat, Highly sensitive kinetic spectrophotometric determination of vanadium based on the oxidation of 2,3,4-trihydroxybenzoic acid with bromate. Mon. für Chem. 143 (2012) 527–534.
26
[27] K.F. Fawy, A.I. Al-Sayed, and A.M. Idris, Developing an ultra-sensitive catalytic spectrophotometric method for vanadium determination in virgin and used lubricating oils, Petr. Chem. 61 (2021) 220–230.
27
[28] S.B. Mathew, G. Pataila, A.K. Pillai, and V.K. Gupta, Direct and selective spectrophotometric method for the determination of vanadium in steel, environmental and biological samples, Spectrochim. Acta (A) 81 (2011) 774–777.
28
[29] Y. Takagai, H. Yamaguchi, T. Kubota, and S. Igarashi, Selective visual determination of vanadium(V) ion in highly acidic solution using desferrioxamine B immobilization cellulose, Chem. Lett. 36 (2006) 136–137.
29
[30] G.M. Mastoi, M.Y. Khuhawar, and R.B. Bozdar, Spectrophotometric determination of vanadium in crude oil, J. Quant. Spect. Rad. Trans. 102 (2006) 236–240.
30
[31] A. Sao, A. Pillai, and V. Gupta, Spectrophotometric determination of vanadium using rhodamine-B, J. Indian Chem. Soc. 83 (2006) 400–402.
31
[32] T.N. Kiran Kumar, and H.D. Revanasiddappa, Spectrophotometric determination of vanadium using variamine blue and its application to synthetic, environmental and biological samples, J. Iran. Chem. Soc. 2 (2005) 161–167.
32
[33] V. Srilalitha, A.R.G. Prasad, V. Seshagiri, and L. Ravindranath, Spectrophotometric determination of trace amounts of vanadium(V) using salicylaldehyde acetoacetic acid hydrazone. Applications Analele Universitatii din Bucuresti Chimie. 1 (2010) 69–76.
33
[34] K. Oguma, O. Yoshioka, J. Noro, and H. Sakurai, Simultaneous determination of vanadium(IV) and vanadium(V) by flow injection analysis using kinetic spectrophotometry with xylenol orange, Talanta 96 (2012) 44–49.
34
[35] T.S-Bahchevanska, N. Milcheva, S. Zaruba, V. Andruch, V. Delchev, K. Simitchiev, and K. Gavazov, A green cloud-point extraction-chromogenic system for vanadium determination, J. Mol. Liq. 248 (2017) 135–142.
35
[36] H. Filik, and Z. Yanaz, A sensitive method for determining total vanadium in water samples using colorimetric-solid-phase extraction-fiber optic reflectance spectroscopy, J. Hazard. Mat. 172 (2009) 1297–1302.
36
[37] A.P. Santos, and V.A. Lemos, Determination of vanadium levels in seafood using dispersive liquid-liquid microextraction and optical sensors. Water Air Soil Pollut. 226 (2015) 60–67.
37
[38] N.P. Milcheva, F. Genc, P.V. Racheva, V.B. Delchev, V. Andruch, and K.B. Gavazov, An environmentally friendly cloud point extraction–spectrophoto-metric determination of trace vanadium using a novel reagent, J. Mol. Liq. 334 (2021) 1160-86.
38
[39] S. Nunes, M.G.A. Korn, and V.A. Lemos, A novel direct-immersion single-drop microextraction combined with digital colorimetry applied to the determination of vanadium in water Leane, Talanta 224 (2021) 1218-93.
39
[40] S. Rastegarzadeh, and V. Rezaei, An optical sensor for zinc determination based on Zincon as sensing reagent, Sen. Actuators (B) 129 (2008) 327–331.
40
[41] S. Rastegarzadeh, and V. Rezaei, A Silver optical sensor based on 5(p-dimethylamino benzylidene) rhodanine immobilized on a triacetylcellulose membrane, J. Anal. Chem. 63 (2008) 897–901.
41
[42] P.C.A. Jeronimo, A.N. Araujo, M. Conceic, and B.S.M. Montenegro, Optical sensors and biosensors based on sol–gel films, Talanta 72 (2007) 13–27.
42
[43] C. McDonagh, C.S. Burke, and B.D. MacCraith, Optical chemical sensors, Chem. Rev. 108 (2008) 400–422.
43
[44] H.G. Floch, and P.F. Belleville, A scratch-resistant single-layer antireflective coating by a low temperature sol-gel route, J. Sol–Gel Sci. Technol. 1 (1994) 293–304.
44
[45] B.D. MacCraith, C.M. McDonagh, G. OKecffe, E.T. Keyes, J.G. Vos, B. OKelly, and J.F. McGilp, Fiber optic oxygen sensor based on fluorescence quenching of evanescent-wave excited ruthenium complexes in sol-gel derived porous coatings, Analyst 118 (1993) 385–388.
45
[46] R.A. Doong, and H.C. Tsai, Immobilization and characterization of sol–gel-encapsulated acetylcholinesterase fiber-optic biosensor, Anal. Chim. Acta 434 (2001) 239–246.
46
[47] D. Avnir, D. Levy, and R. Reisfield, The nature of the silica cage as reflected by spectral changes and enhanced photostability of trapped Rhodamine 6G, J. Phys. Chem. 88 (1984) 5956–5959.
47
[48] C. McDonagh, F. Sheridan, T. Butler, and B.D. MacCraith, Characterisation of sol-gel-derived silica films, J. Non-Cryst. Solids 194 (1996) 72–77.
48
[49] Y. Tang, E.C. Tehan, Z, Tao, and F.V. Bright, Sol−gel-derived sensor materials that yield linear calibration plots, high sensitivity, and long-term stability, Anal. Chem. 75 (2003) 2407–2413.
49
[50] A.S. Amin, T.Y. Mohammed, and A.A. Mousa, Spectrophotometric studies and applications for the determination of yttrium in pure and in nickel base alloys, Spectrochim. Acta (A) 59 (2003) 2577–2584.
50
[51] A.S. Amin, and M.Y. Nassar, Cloud-point extraction for preconcentration and platinum determination using spectrophotometry in environmental samples, Anal. Chem. Lett. 7 (2017) 128–141.
51
[52] A.I. Vogel, A Textbook of Quantitative Inorganic Analysis, 5th edn.; Longman: London, (1979).
52
[53] J.M. Bosque-Sendra, M.C. Valencia, and S. Boudra, Speciation of vanadium (IV) and vanadium (V) with Eriochrome Cyanine R in natural waters by solid phase spectrophotometry, Fresenius J. Anal. Chem. 360 (1998) 31–37.
53
[54] A.P. Kumar, P.R. Reddy, and V.K. Reddy, A rapid, simple, and sensitive spectrophotometric determination of traces of vanadium(V) in foodstuffs, alloy steels, and pharmaceutical, water, soil, and urine samples, Anal. Lett. 41 (2008) 1022–1037.
54
[55] B.R. Reddy, P. Radhika, J.R. Kumar, D.N. Priya, and K. Rajgopal, Extractive spectrophotometric determination of cobalt(II) in synthetic and pharmaceutical samples using Cyanex 923, Anal. Sci. 20 (2004) 345–349.
55
[56] R.O. Molatlhegi, M. Sc. Thesis. Faculty of Natural Sciences. Tshwane University of Technology, (2005).
56
[57] M. Swetha, R.P. Raveendra, R.V. Krishna, Direct derivative spectrophoto-metric determination of micro amounts of Vanadium(V) by 5-bromo salicylaldehyde isonicotinoyl hydrazone (5-BrSAINH), Inter. J. Chem. Tech. Res. 5 (2013) 2322–2328.
57
[58] B. Lokeshappa, S. Kandarp, T. Vivek, and K.D. Anil, Assessment of toxic metals in agricultural products, Food and Public Health 2 (2012) 24–29.
58
[59] A.S. Amin, M.A. Kassem, and T.Y. Mohammed, Utilization of cloud-point extraction for colorimetric determination of trace amounts of thorium(IV) in real samples, RSC Adv. 5 (2015) 52095–52100.
59
[60] A.S. Amin, Application of a triacetylcellulose membrane with immobilized of 5-(2‘,4‘-dimethylphenylazo)-6-hydroxypyrimidine-2,4-dione for mercury determination in real samples, Sens. Actuators (B), 221 (2015) 1342–1347.
60
[61] A. Abbaspour, and R. Mirzajani, Application of spectral β-correction method and partial least squares for simultaneous determination of V(IV) and V(V) in surfactant media, Spectrochim. Acta (A) 64 (2006) 646–652.
61
[62] N. Agnihotri, R. Dass, and J.R. Mehta, 3-Hydroxy-2-(2-thienyl)-4H-chromen-4-one as an analytical reagent for spectrophotometric determination of vanadium (V), J. Indian. Chem. Soc. 75 (1998) 514–515.
62
[63] H. Tavallali, R. and Nejabatm, Developing fast and facile method for speciation analysis of vanadium(V/IV) ions with calmagite immobilization on triacetyl cellulose membrane in water samples, J. Braz. Chem. Soc. 26 (2015) 592–599.
63
[64] M.A. Alk, A.A. El-Asmy, and W.M. Yossef, Separation via flotation, spectrophotometric speciation, and determination of vanadium (IV) in wastes of power stations. Anal. Sci. 21 (2005) 1325–1335.
64
[65] IUPAC Nomenclature, symbols, units and their usage in spectrochemical analysis—I. General atomic emission spectroscopy Analytical chemistry division, Spectrochim. Acta (B) 3 (1978) 241–245.
65
[66] J.N. Miller, and J.C. Miller, Statistics and Chemometrics for Analytical Chemistry, 5th edn, Prentice-Hall, England, (2005).
66
ORIGINAL_ARTICLE
Metal Determination in Iranian Saffron
The present investigation reports a quantitative analysis of metals in the saffron samples collected from seven different saffron production areas in the Khorasan Razavi province, Iran. Khorasan Razavi is the leading producer of saffron in Iran, and more than 95% of the global production of this expensive spice is attributed to Iran. Since environmental pollution is increasing, saffron is contaminated with various organic and inorganic contaminants such as heavy metals. Twenty-one saffron samples were collected in the flowering season of 2018 and analyzed for metal content. The concentration of microelements and heavy metals including Zn, Fe, Ca, Mn, Mg, Na, K, Pb, Cd, Cu, and Cr was determined in the samples collected from three farms in each production area with graphite furnace and flame atomic absorption spectroscopy. The results revealed that the collected saffron stigmas contain a wide range of minerals and heavy metals with different concentrations. Potassium is the most abundant element, and Cd had the least concentration in the saffron. It can be concluded that ecological management plans such as reducing chemical fertilizers and improving organic fertilizers can decline the extent of heavy metals in the saffron.
https://ijac.journals.pnu.ac.ir/article_7798_5d72c82d91757bedd7eb298c0b924ba3.pdf
2021-03-01
78
86
10.30473/ijac.2021.59010.1186
Saffron
heavy metal
Atomic absorption spectroscopy
Khorasan Razavi
Javad
Feizy
j.feizy@rifst.ac.ir
1
Department of Food Safety and Quality Control, Research Institute of Food Science and Technology, P. O. Box 91735-147, Mashhad, Iran.
LEAD_AUTHOR
Sima
Ahmadi
sima.ahmadi90@yahoo.com
2
Department of Food Safety and Quality Control, Research Institute of Food Science and Technology, P. O. Box 91735-147, Mashhad, Iran.
AUTHOR
Moslem
Jahani
moslemjahani@yahoo.com
3
Department of Food Chemistry, Research Institute of Food Science and Technology. Mashhad, Iran.
AUTHOR
R.
Lakshmipathy
lakshmipathy.vit@gmail.com
4
Department of Chemistry, KCG College of Technology, Chennai, Tamil Nadu, India – 600097.
AUTHOR
[1] P. Goldblatt, T.J. Davies, J.C. Manning, M. van der Bank and V. Savolainen, Phylogeny of Iridaceae Subfamily Crocoideae Based on a Combined Multigene Plastid DNA Analysis. Aliso 22(1) (2006):Article 32.
1
[2] S.R. Sampathu, S. Shivashankar, Y.S. Lewis and A.B. Wood, Saffron (Crocus Sativus Linn.) — Cultivation, processing, chemistry and standardization. Crit. Rev. Food Sci. Nutr. 20(2) (1984) 123-157.
2
[3] H. Hosseinzadeh and H.M. Younesi, Antinociceptive and anti-inflammatory effects of Crocus sativus L.stigma and petal extracts in mice. BMC Pharmacol. 2 (2002) 7-15.
3
[4] H. Caballero-Ortega, R. Pereda-Miranda, L. Riverón-Negrete, J.M. Hernández, M. Medécigo-Ríos, A. Castillo-Villanueva and F.I. Abdullaev, Chemical composition of saffron (Crocus sativus L.) from four countries. In, 2004. International Society for Horticultural Science (ISHS), Leuven, Belgium, pp 321-326.
4
[5] M. Kafi, A. Koocheki and M.H. Rashed, Saffron (Crocus Sativus): Production and Processing. Taylor & Francis, CRC Press; 1st edition (2006) pp 1-252.
5
[6] A. Mollafilabi, Comparative study of q new method of saffron cultivation with a traditional method for improving saffron productivity. Paper presented at the III International Symposium on Saffron: Forthcoming Challenges in Cultivation, Research and Economics, (2010).
6
[7] F.I. Abdullaev, Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.). Exp. Biol. Med 227 (2002) 20-25.
7
[8] J.A. Fernandez, Biology, biotechnology and biomedicine of saffron. Recent research developments in plant science, Research Signpost, Trivandrum 2 (2004) pp127-159.
8
[9] M. Ajami, S. Eghtesadi, H. Pazoki-Toroudi, R. Habibey and S.A. Ebrahimi, Effect of crocus sativus on gentamicin induced nephrotoxicity. Biol. Res. 43 (2010) 83-90.
9
[10] C.D. Kanakis, P.A. Tarantilis, H.A. Tajmir-Riahi and M.G. Polissiou, Crocetin, Dimethylcrocetin, and Safranal Bind Human Serum Albumin: Stability and Antioxidative Properties. J. Agric. Food Chem. 55(3) (2007) 970-977.
10
[11] S.A. Ordoudi, C.D. Befani, N. Nenadis, G.G. Koliakos and M.Z. Tsimidou, Further Examination of Antiradical Properties of Crocus sativus Stigmas Extract Rich in Crocins. J. Agric. Food Chem. 57(8) (2009) 3080-3086.
11
[12] A.K. Sharma, A Handbook of Organic Farming. Agrobios (India), India (2001) pp 1-11.
12
[13] A. Kumar, A.G.C Nair,. A.V.R. Reddy and A.N. Garg, Availability of essential elements in Indian and US tea brands. Food Chem. 89(3) (2005) 441-448.
13
[14] A. Łozak, K. Sołtyk, P. Ostapczuk and Z. Fijałek, Determination of selected trace elements in herbs and their infusions. Sci. Total Environ. 289(1) (2002) 33-40.
14
[15] X. Cao, G. Zhao, M. Yin and J. Li, Determination of ultratrace rare earth elements in tea by inductively coupled plasma mass spectrometry with microwave digestion and AG50W-x8 cation exchange chromatography. Analyst 123(5) (1998) 1115-1119.
15
[16] D.A. Blake, R.M. Jones, R.C. Blake, A.R.P. avlov, I.A. Darwish and H.Yu, Antibody-based sensors for heavy metal ions. Biosens. Bioelectron. 16(9) (2001) 799-809.
16
[17] S.C. Wong, X.D. Li, G. Zhang, S.H. Qi and Y.S. Min, Heavy metals in agricultural soils of the Pearl River Delta, South China. Environ. Pollut. 119(1) (2002) 33-44.
17
[18] D.C. Adriano, W.W. Wenzel, J. Vangronsveld and N.S. Bolan, Role of assisted natural remediation in environmental cleanup. Geoderma 122(2) (2004) 121-142.
18
[19] M.R. Behnia, Saffron cultivation, vol 1. Tehran university publication, Tehran (1991) pp 1-530.
19
[20] S. Ikram, U. Habib and N. Khalid, Effect of different potting media combinations on growth and vase life of tuberose (Polianthes tuberosa Linn.). Pak. J. Agric. Sci. 49 (2012) 121-125.
20
[21] A.R. Koocheki, M.A. Behdani, M. Nassiri Mahallati and P. Rezvani Moghaddam, The Evaluation of Quantitative Relationships between Saffron Yield and Nutrition (On farm trial). J. Iranian Field Crops Res. 3 (2005) 14-11.
21
[22] Y.Y. Murevanhema and V.A. Jideani, Potential of Bambara Groundnut (Vigna subterranea (L.) Verdc) Milk as a Probiotic Beverage-A Review. Crit. Rev. Food Sci. Nutr. 53(9) (2013) 954-967.
22
[23] C.Q. Wang and H. Song, Calcium protects Trifolium repens L. seedlings against cadmium stress. Plant Cell Rep. 28(9) (2009) 1341-1349.
23
[24] J. Ahmadi, M.M. Seyfi and M. Amini, Effect of spraying micro nutrients Fe, Zn and Ca on grain and oilyield of sesame (Sesamusindicum L.) varieties. J. Crop Prod. 5(3) (2012) 115-130.
24
[25] A. Vatanpur-Azghadi and N. Mojtahedi, A review on application of tissue culture and biotechnology in saffron. Paper presented at the Proceeding of 3rd National Congress on Saffron, 11-12th December (2003), Mashhad, Iran.
25
[26] J.L. Havlin, S.L. Tisdale, W.L. Nelson and J.D. Beaton, Soil fertility and fertilizers : an introduction to nutrient management. Boston : Pearson, (2014).
26
[27] L.X. Zhou and J.W.C. Wong, Effect of Dissolved Organic Matter from Sludge and Sludge Compost on Soil Copper Sorption. J. Environ. Qual. 30 (2001) 878-883.
27
[28] D.J. Walker, R. Clemente, A. Roig, and M. Bernal, The effects of soil amendments on heavy metal bioavailability in two contaminated Mediterranean soils. Environ. Pollut. 122(2) (2003) 303-312.
28
[29] M. Taghipour, M. Khademi and S. Ayoubi, Spatial variability of Pb and Zn concentration and itsrelationship with land use and parent materials in selected surface soils of Hamadan province. J. Soil Water Conserv. 24(1) (2010) 132-144.
29
[30] E. Nelson, Principles of Environmental Geochemistry. Cengage Learning, Inc, CA, United States (2003).
30
[31] M. Shokrzadeh and S.S. Saeedi Saravi, The study of heavy metals (zinc, lead, cadmium, and chromium) in water sampled from Gorgan coast (Iran), Spring 2008. Toxicol. Environ. Chem. 91(3) (2009) 405-407.
31
[32] S. Kamala-Kannan, B. Prabhu Dass Batvari, K.J. Lee, N. Kannan, R. Krishnamoorthy, K. Shanthi and M. Jayaprakash, Assessment of heavy metals (Cd, Cr and Pb) in water, sediment and seaweed (Ulva lactuca) in the Pulicat Lake, South East India. Chemosphere 71(7) (2008) 1233-1240.
32
[33] M. Rostami, R. Karamian and Z. Joulaei, Effect of Different Heavy Metals on Physiological Traits of Saffron (Crocus sativus L.). Saffron Agronomy Technol. 3(2) (2015) 83-96.
33
[34] L. Brahim and M. Mohamed, Effects of copper stress on antioxidative enzymes, chlorophyll and protein content in Atriplexhalimus. African J. Biotechnol. 10(50) (2011) 10143-10148.
34
[35] INSO 259-1. Saffron-Specification. 2013. 5th revision, Iranian National Standard Organization.
35
[36] C. Micó, L. Recatalá, M. Peris and J. Sánchez, Assessing heavy metal sources in agricultural soils of an European Mediterranean area by multivariate analysis. Chemosphere 65(5) (2006) 863-872.
36
[37] H. Rodríguez, R. Fraga, T. Gonzalez and Y. Bashan, Genetics of phosphate solubilization and its potential applications for improving plant growth-promoting bacteria. In, Dordrecht, 2007. First International Meeting on Microbial Phosphate Solubilization. Springer Netherlands, pp 15-21.
37
[38] E. Islam, D. Liu, T. Li, X. Yang, X. Jin, Q. Mahmood, S. Tian and J. Li, Effect of Pb toxicity on leaf growth, physiology and ultrastructure in the two ecotypes of Elsholtzia argyi. J. Hazard. Mater. 154(1) (2008) 914-926.
38
[39] R. John, P. Ahmad, K. Gadgil and S. Sharma, Heavy metal toxicity: Effect on plant growth, biochemical parameters and metal accumulation by Brassica juncea L. Int. J. Plant Prod. 3(3) (2012) 65-76.
39
[40] Y. Rui, J. Shen and F. Zhang, Application of ICP-MS to determination of heavy metal content of heavy metals in two kinds of N fertilizer. Guang Pu Xue Yu 28(10) (2008) 2425-2427.
40
[41] M. Molina, F. Aburto, R. Calderón, M. Cazanga and M. Escudey, Trace Element Composition of Selected Fertilizers Used in Chile: Phosphorus Fertilizers as a Source of Long-Term Soil Contamination. J. Soil Contam. 18(4) (2009) 497-511.
41
[42] M.B. McBride and G. Spiers, Trace element content of selected fertilizers and dairy manures as determined by ICP–MS. Comm. Soil Sci. Plant Anal. 32(1-2) (2001) 139-156.
42
[43] X.T. Ju, C.L. Kou, P. Christie, Z.X. Dou and F.S. Zhang, Changes in the soil environment from excessive application of fertilizers and manures to two contrasting intensive cropping systems on the North China Plain. Environ. Pollut. 145(2) (2007) 497-506.
43
[44] Y. Jiao, C.A. Grant and L.D. Bailey, Effects of phosphorus and zinc fertilizer on cadmium uptake and distribution in flax and durum wheat. J. Sci. Food Agric. 84(8) (2004) 777-785.
44
[45] L-H. Jia and Y. Liu, Determination of the major metal elements including heavy metals in Saffron from Tibet and Henan by ICP-AES or ICP-MS. J. Chin. Pharm. Sci. 20 (2011) 297-301.
45
[46] J.P. Melnyk, S. Wang and M.F. Marcone, Chemical and biological properties of the world's most expensive spice: Saffron. Food Res. Int. 43(8) (2010) 1981-1989.
46
ORIGINAL_ARTICLE
Molybdenum Disulfide/Graphene Oxide Nanohybrid as an Electrocatalyst for Sensitive Detection of Carbamazepine in Human Body Fluid Samples
Molybdenum disulfide as a transition metal dichalcogenide was prepared by a hydrothermal method and hybridized with graphene oxide (MoS2/GO). The as-prepared materials were investigated by Fourier transform infra-red spectroscopy (FT-IR), X-ray diffraction (XRD), energy dispersive X-ray elemental analysis (EDX) techniques as well transmission electron microscopy (TEM) image. The nanomaterial with its electrocatalytic properties was applied as an electro-nanocatalyst for loading on a glassy carbon electrode (MoS2/GO-GCE) for detection of carbamazepine as an anti-epileptic in real body samples. The simple and low-cost developed electrochemical sensor detected carbamazepine with a vast linear concentration range(30-350nM), very low detection limit about 6.0nM and significant sensitivity equal to 0.134µA/nM.
https://ijac.journals.pnu.ac.ir/article_7819_34e17a381bacd6e8cf4990e84def70ec.pdf
2021-03-01
87
92
10.30473/ijac.2021.59425.1195
Carbamazepine
Transition metal dichalcogenides
Electrocatalyst
Sensor
Amirkhosro
Beheshti
amirkhosro_b@yahoo.com
1
Department of Chemistry, Payame Noor University, PO Box 19395-4697, Tehran, Iran
LEAD_AUTHOR
Tahereh
Rohani
th_rohani@yahoo.com
2
Department of Chemistry, Payame Noor University, PO Box 19395-4697, Tehran, Iran
AUTHOR
Sayed Zia
Mohammadi
szmohammadi@yahoo.com
3
Department of Chemistry, Payame Noor University, PO Box 19395-4697, Tehran, Iran
AUTHOR
Maryam
Dadkhodazadeh
maryamdadkhoda0@gmail.com
4
Department of Chemistry, Payame Noor University, PO Box 19395-4697, Tehran, Iran
AUTHOR
[1] F.J.E. Vajda, S. Hollingworth, J. Graham, A.A. Hitchcock, T.J. O’Brien, C.M. Lander, M.J. Eadie, Changing patterns of antiepileptic drug use in pregnant Australian women. Acta Neurol. Scand, 2 (2010) 89-93.
1
[2] G. Özer, Y. Ünal, G. Kutlu, Y.B. Gömceli, L.E. İnan, A retrospective analysis of restless legs syndrome in epileptic patients, ACEM, 1 (2018) 15-17.
2
[3] M. Vosough, S. Ghafghazi, M. Sabetkasaei, Chemometrics enhanced HPLC–DAD performance for rapid quantification of carbamazepine and phenobarbital in human serum samples, Talanta, 119(2014) 17-23.
3
[4] S. Ghafghazi, T.M. Zanjani, M. Vosough, M. Sabetkasaei, Interference-free determination of carbamazepine in human serum using high performance liquid chromatography:a comprehensive research with three-way calibration methods, IJPR, 1 (2017) 120.
4
[5] H. Breton, M. Cociglio, F. Bressolle, H. Peyriere, J.P. Blayac, D. Hillaire-Buys, Liquid chromatography–electrospray mass spectrometry determination of carbamazepine, oxcarbazepine and eight of their metabolites in human plasma, J. Chromatogr, 2 (2005) 80-90.
5
[6] T.A. Rodina, E.S. Mel’Nikov, A.V. Sokolov, A.B. Prokof’Ev, V.V. Arkhipov, A.A. Aksenov, D.L. Pozdnyakov, Rapid HPLC-MS/MS determination of carbamazepine and carbamazepine-10, 11-epoxide, Pharm. Chem. J, 6 (2016) 419-423.
6
[7] C. Huang, Q. He, H. Chen, Flow injection photochemical spectrofluorimetry for the determination of carbamazepine in pharmaceutical preparations, J Pharm Biomed Anal, 1 (2002) 59-65.
7
[8] G.M. Escandar, D.G. Gómez, A.E. Mansilla, A.M. de la Peña, H.C. Goicoechea, Determination of carbamazepine in serum and pharmaceutical preparations using immobilization on a nylon support and fluorescence detection, Anal. Chim. Acta, 2 (2004) 161-170.
8
[9] B. Hemmateenejad, Z. Rezaei, S. Khabnadideh, M. Saffari, A PLS-based extractive spectrophotometric method for simultaneous determination of carbamazepine and carbamazepine-10, 11-epoxide in plasma and comparison with HPLC, Spectrochim. Acta A Mol. Biomol. Spectrosc, 3 (2007) 718-724.
9
[10] Z. Rezaei, B. Hemmateenejad, S. Khabnadideh, M. Gorgin, Simultaneous spectrophotometric determination of carbamazepine and phenytoin in serum by PLS regression and comparison with HPLC, Talanta, 1 (2005) 21-28.
10
[11] M. A. García-García, O. Dominguez-Renedo, A. Alonso-Lomillo, Arcos-Martínez, M. J. Electrochemical methods of carbamazepine determination, Sens. Lett, 4 (2009), 586-591.
11
[12] S.S. Kalanur, J. Seetharamappa, Electrochemical oxidation of bioactive carbamazepine and its interaction with DNA, Anal. Lett, 4 (2010) 618-630.
12
[13] H.Y. Wang, M.L. Pan, Y.O. Su, S.C. Tsai, C. H. Kao, S.S. Sun, W.Y, Comparison of Differential Pulse Voltammetry (DPV)—a new method of carbamazepine analysis—with Fluorescence Polarization Immunoassay (FPIA), J.Electroanal. Chem, 4(2011) 415-420.
13
[14] F. Zaviska, P. Drogui, J.F. Blais, G. Mercier, P. Lafrance, Experimental design methodology applied to electrochemical oxidation of the herbicide atrazine using Ti/IrO2 and Ti/SnO2 circular anode electrodes, J. Hazard. Mater., 2 (2011) 1499-1507.
14
[15] M. Fathi, M.S. Safavi, S. Mahdavi, S. Mirzazadeh, V. Charkhesht, A. Mardanifar, M. Mehdipour, Co–P alloy matrix composite deposits reinforced by nano-MoS2 solid lubricant: An alternative tribological coating to hard chromium coatings, Tribol. Int, 159 (2021) 106956.
15
[16] Y.H. Wang, K.J. Huang, X. Wu, Recent advances in transition-metal dichalcogenides based electrochemical biosensors: A review, Biosens. Bioelectron, 97 (2017) 305-316.
16
[17] Y.H. Wang, L.L. He, K.J. Huang, Y.X. Chen, S.Y. Wang, Z.H. Liu, D. Li, Recent advances in nanomaterial-based electrochemical and optical sensing platforms for microRNA assays, ANLST, 9 (2019) 2849-2866.
17
[18] A. Lerf, H. He, M. Forster, J. Kalinowski, Structure of graphite oxide revisited, J. Phys. Chem. B, 23 (1998) 4477-4482.
18
[19] Z. Wang, L. Ma, W. Chen, G. Huang, D. Chen, L. Wang, J.Y. Lee, Facile synthesis of MoS 2/graphene composites: effects of different cationic surfactants on microstructures and electrochemical properties of reversible lithium storage, RSC Adv, 44 (2013) 21675-21684.
19
[20] S.S. Kalanur, J. Seetharamappa, Electrochemical oxidation of bioactive carbamazepine and its interaction with DNA, Anal. Lett,43 (2010) 618-630.
20
ORIGINAL_ARTICLE
Electrochemical Determination of Chloramphenicol in Milk and Eye-drop Using Easily Activated Screen Printed Carbon Electrodes
An analytical method that offers fast response with a cheap instrument and simple sample preparation is an ideal technique that is required in scientific analysis. Electrochemical sensing is an analytical method that suits the above criteria to determine various samples using different electrode material. Detection of chloramphenicol in agricultural products and drug samples using cheap electrode materials is highly required due to its wide application in agriculture. In this study a cost-effective activated SPCE was made electrochemically to determine chloramphenicol in eye-drop and pasteurized milk. The activation of the SPCE was straightforward and done by cycling 0.5 M KOH using LSV techniques. Surface imaging, spectroscopy, and electrochemical analyses showed that there is an effective formation of new functional groups during the activation. The activated SPCE gave a higher peak current for Chloramphenicol during the CV and SWV study using PBS pH 6.5 compared to that of the bare one. Utilizing the optimal SWV conditions, a linear calibration curve was obtained in the range of 0.05‒100 µM with quite a small detection limit of 20 nM. In addition to the high sensitivity, stability, and remarkable recovery, the excellent reproducibility makes the activated SPCE applicable in real sample analysis.
https://ijac.journals.pnu.ac.ir/article_7855_a2ead8d418424a1bce4c4104b948e672.pdf
2021-03-01
93
101
10.30473/ijac.2021.59391.1191
Chloramphenicol
Screen Printed Carbon Electrode
Electrochemical
Stable
Activated
Tesfu
Hailu
tesfu.hailu@aastu.edu.et
1
Department of industrial chemistry, Addis Ababa Science and Technology University, Addis Ababa P.O.Box 16417, Ethiopia.
LEAD_AUTHOR
Yaw-Kuen
Li
nctuykl@g2.nctu.edu.tw
2
Department of applied chemistry, 1001 University Road, Hsinchu, Taiwan 300, ROC
AUTHOR
Merid
Tessema
tessemamerid@yahoo.com
3
Department of chemistry, Addis Ababa University College of Natural and Computational Science, Addis Ababa P.O.Box 1176, Ethiopia.
AUTHOR
[1] W.F. Bansode. K.R. Singh. and P. Shukla. Chloramphenicol Toxicity: A Review. J. Med. Med. Sci. 2 (13) (2011) 1313-1316.
1
[2] A.Y. Adel. CHLORAMPHENICOL: Relation of Structure to Activity and Toxicity. Ann. Rev. Pharmacol. Toxicol. 128 (1998) 83-100.
2
[3] C.M. Roberts. Antibiotic toxicity, interactions and resistance development. Periodontology 2000. 28 (2002) 280–297.
3
[4] S. Goel. Antibiotics in the Environment: A Review. ACS Symposium Series Emerging Micro-Pollutants in the Environment: Occurrence, Fate and Distribution. (2015) 19–42.
4
[5] P.A. Guy. D. Royer. P. Mottier. E. Gremaud. A. Perisset. and R.H. Stadler. Quantitative determination of chloramphenicol in milk powders by isotope dilution liquid chromatography coupled to tandem mass spectrometry. J. Chromatogr. A. 1054 (2004) 365–371.
5
[6] L.K. Sørensen. T.H. Elbæk. and H. Hansen. Determination of Chloramphenicol in Bovine Milk by Liquid Chromatography/Tandem Mass Spectrometry. J. AOAC Int. 86 (2003) 703–706.
6
[7] X. Wu. X. Tian. L. Xu. J. Li. X. Li. and Y. Wang. Determination of Aflatoxin M1 and Chloramphenicol in Milk Based on Background Fluorescence Quenching Immunochromatographic Assay. Biomed Res. Int. (2017) 1–7.
7
[8] S.-I. Kawano. H.-Y. Hao. Y. Hashi. and J.-M. Lin. Analysis of chloramphenicol in honey by on-line pretreatment liquid chromatography–tandem mass spectrometry. Chin. Chem. Lett. 26 (2015) 36–38.
8
[9] F. Barreto. C. Ribeiro. R.B. Hoff. and T.D. Costa. Determination and confirmation of chloramphenicol in honey, fish and prawns by liquid chromatography–tandem mass spectrometry with minimum sample preparation: validation according to 2002/657/EC Directive. Food Addit Contama A. 29 (2012) 550–558.
9
[10] A. Aresta. D. Bianchi. C. Calvano. and C. Zambonin. Solid phase microextraction—Liquid chromatography (SPME-LC) determination of chloramphenicol in urine and environmental water samples. J. Pharm. Biomed. Anal. 53 (2010) 440–444.
10
[11] A. Gantverg. I. Shishani. and M. Hoffman. Determination of chloramphenicol in animal tissues and urine. Analytica Chimica Acta. 483 (2003) 125–135.
11
[12] M. Rejtharová. and L. Rejthar. Determination of chloramphenicol in urine, feed water, milk and honey samples using molecular imprinted polymer clean-up. J. Chromatogr. A. 1216 (2009) 8246–8253.
12
[13] T.A. Hamoudi. and W.A. Bashir. Spectrophotometric Determination of Chloramphenicol in Pharmaceutical Preparations. J. Educ. Sci. 27 (2018) 19–35.
13
[14] Y. Xie. Q. Hu. M. Zhao. Y. Cheng. Y. Guo. H. Qian. and W. Yao. Simultaneous Determination of Erythromycin, Tetracycline, and Chloramphenicol Residue in Raw Milk by Molecularly Imprinted Polymer Mixed with Solid-Phase Extraction. Food Anal. Methods.11 (2017) 374–381.
14
[15] B.W. Blais. A. Cunningham. and H. Yamazaki. Novel immunofluorescence capillary electrophoresis assay system for the determination of chloramphenicol in milk. Food Agric. Immunol. 6 (1994) 409–417.
15
[16] H. Tsai. H.C. Hu. C.C. Hsieh. Y.H. Lu. C.H. Chen. and C.B. Fuh. Fluorescence studies of the interaction between chloramphenicol and nitrogen‐doped graphene quantum dots and determination of chloramphenicol in chicken feed. J. Chin. Chem. Soc. 67 (2019) 152–159.
16
[17] X.-D. Pan. P.-G. Wu. W. Jiang. and B.-J. Ma. Determination of chloramphenicol, thiamphenicol, and florfenicol in fish muscle by matrix solid-phase dispersion extraction (MSPD) and ultra-high pressure liquid chromatography tandem mass spectrometry. Food Control. 52 (2015) 34–38.
17
[18] E. Alechaga. E. Moyano. and M.T. Galceran. Ultra-high performance liquid chromatography-tandem mass spectrometry for the analysis of phenicol drugs and florfenicol-amine in foods. Analyst. 137 (2012) 2486.
18
[19] A. Forti. G. Campana. A. Simonella. M. Multari. and G. Scortichini. Determination of chloramphenicol in honey by liquid chromatography–tandem mass spectrometry. Analytica Chimica. Acta. 529 (2005) 257–263.
19
[20] M. Ashton. HPLC Determination of Chloramphenicol, Chloramphenicol Monosuccinate and Chloramphenicol Glucuronide in Biological Matrices. J. Liq. Chromatogr. 12 (1989) 1719–1732.
20
[21] H.-Y. Shen. and H.-L. Jiang. Screening, determination and confirmation of chloramphenicol in seafood, meat and honey using ELISA, HPLC–UVD, GC–ECD, GC–MS–EI–SIM and GCMS–NCI–SIM methods. Analytica Chimica Acta. 535 (2005) 33–41.
21
[22] T. Menanteau. E. Levillain. and T. Breton. Electrografting via Diazonium Chemistry: From Multilayer to Monolayer Using Radical Scavenger. Chem. Mater. 25 (2013) 2905–2909.
22
[23] C.A. Richard. N.B. Philip. L. Jacek. Electrochemistry of Carbon Electrodes. Adv. Electrochem. Sci. Eng. (2015) 19-35.
23
[24] H. Beitollahi. S.Z. Mohammadi. M. Safaei. and S. Tajik. Applications of electrochemical sensors and biosensors based on modified screen-printed electrodes: a review. Anal. Methods. 12 (2020) 1547–1560.
24
[25] H.M. Mohamed. Screen-printed disposable electrodes: Pharmaceutical applications and recent developments. Trends Analyt Chem. 82 (2016) 1–11.
25
[26] A. Ambrosi. R. Antiochia. L. Campanella. R. Dragone. and I. Lavagnini. Electrochemical determination of pharmaceuticals in spiked water samples. J. Hazard. Mater. 122 (2005) 219–225.
26
[27] T. Gan. J. Li. H. Li. Y. Liu. and Z. Xu. Synthesis of Au nanorod-embedded and graphene oxide-wrapped microporous ZIF-8 with high electrocatalytic activity for the sensing of pesticides. Nanoscale. 11 (2019) 7839–7849.
27
[28] M.M. Athar. and M. Zaib. Electrochemical Evaluation of Phanerocheaete Chrysosporium Based Carbon Paste Electrode with Potassium Ferricyanide Redox System. Int. J. Electrochem. Sci. 10 (2015) 6690 – 6702.
28
[29] B.V.M. Zanoni. V.L.I. Rosa. R.C. Pesquero. and R.N. Stradiotto. Electrochemical Behavior of a Nitrobenzenesulfonyl Derivative of Aniline in Aqueous Solution. J. Braz. Chem. Soc. 8 (1997) 223-227.
29
[30] N. Sebastian. W.-C. Yu. and D. Balram. Electrochemical detection of an antibiotic drug chloramphenicol based on a graphene oxide/hierarchical zinc oxide nanocomposite. Inorg. Chem. Front. 6 (2019) 82–93.
30
[31] L. Xiao. R. Xu. Q. Yuan. and F. Wang. Highly sensitive electrochemical sensor for chloramphenicol based on MOF derived exfoliated porous carbon. Talanta. 167 (2017) 39–43.
31
[32] B. Uslu. B.D. Topal. and S.A. Ozkan. Electroanalytical investigation and determination of pefloxacin in pharmaceuticals and serum at boron-doped diamond and glassy carbon electrodes. Talanta. 74 (2015) 1191–1200.
32
[33] Y.-M. Xia. W. Zhang. M.-Y. Li. M. Xia. L.-J. Zou. and W.-W. Gao. Effective Electrochemical Determination of Chloramphenicol and Florfenicol Based on Graphene/Copper Phthalocyanine Nanocomposites Modified Glassy Carbon Electrode. J. Electrochem. Soc. 166 (2019) B654-B663.
33
[34] K. Kor. and K. Zarei. Electrochemical determination of chloramphenicol on glassy carbon electrode modified with multi-walled carbon nanotube–cetyltrimethylammonium bromide–poly(diphenylamine). J. Electroanal. Chem. 733 (2014) 39–46.
34
[35] Y. Yuan. X. Xu. J. Xia. F. Zhang. Z. Wang. and Q. Liu. A hybrid material composed of reduced graphene oxide and porous carbon prepared by carbonization of a zeolitic imidazolate framework (type ZIF-8) for voltammetric determination of chloramphenicol. Microchimica Acta. 186 (2019) 1-8.
35
[36] T. Sun. H. Pan. Y. Mei. P. Zhang. D. Zeng. X. Liu. S. Rong. and D. Chang. Electrochemical sensor sensitive detection of chloramphenicol based on ionic-liquid-assisted synthesis of de-layered molybdenum disulfide/graphene oxide nanocomposites. J. Appl. Electrochem. 49 (2018) 261–270.
36
[37] W. Yi. Z. Li. C. Dong. H.-W. Li. and J. Li. Electrochemical detection of chloramphenicol using palladium nanoparticles decorated reduced graphene oxide. Microchem. J. 148 (2019) 774–783.
37
ORIGINAL_ARTICLE
Preparation of Acridine Orange-MWCNT Modified Electrode for Voltammetric Detection of Dopamine in the Presence of Ascorbic Acid
Acridine orange supported on multi-walled carbon nanotube (MWCNT) is used for modification of carbon-paste electrode. The studies show that acridine orange efficaciously immobilized in the matrix of the electrode by applying nafion/MWCNT composite under the ultrasonic condition. The results of voltammetric experiments demonstrate that the prepared electrode has an effective response to DA and AA and a relatively big anodic peak separation (nearly 368 mV) is obtained for these compounds. Good sensitivity and selectivity and very low detection limit (0.03 µM) makes the modified electrode very effective in the manufacture of simple devices for the concurrent detection of dopamine in the presence of ascorbic acid in clinical and pharmaceutical preparations.
https://ijac.journals.pnu.ac.ir/article_7871_11e0a8e226295fc7047a5614e281fab9.pdf
2021-03-01
102
109
10.30473/ijac.2021.59458.1196
Acridine orange
Carbon Nanotube
dopamine
voltammetry
Electrocatalysis
Hamid-Reza
Zare-Mehrjardi
zareanalyst@gmail.com
1
Department of Chemistry, Payame Noor University, PO BOX 19395-3697 Tehran, Iran
LEAD_AUTHOR
[1] E. Demir, Ö. Göktug, R. İnam, D. Doyduk, Development and Characterization of Iron (III) Phthalocyanine Modified Carbon Nanotube Paste Electrodes and Application for Determination of Fluometuron Herbicide as an Electrochemical Sensor, J. Electroanal. Chem. 895 (2021) 115389.
1
[2] E.R. Santana, E.C. Martins, A. Spinelli, Electrode modified with nitrogen-doped graphene quantum dots supported in chitosan for triclocarban monitoring, Microchem. J. 167 (2021) 106297.
2
[3] A. Kumaravel, M. Murugananthan, Electrochemical detection of fenitrothion usingnanosilver/dodecane modified glassy carbon electrode, Sensors Actuators, B Chem. 331 (2021) 129467.
3
[4] H. Silah, C. Erkmen, E. Demir, B. Uslu, Modified indium tin oxide electrodes: Electrochemical applications in pharmaceutical, biological, environmental and food analysis, TrAC - Trends Anal. Chem. 141 (2021) 116289.
4
[5] W. Boumya, N. Taoufik, M. Achak, N. Barka, Chemically modified carbon-based electrodes for the determination of paracetamol in drugs and biological samples, J. Pharm. Anal. 11 (2021) 138–154.
5
[6] S.Nikhil, A. Karthika, P.Suresh, A. Suganthi, M. Rajarajan, A selective and sensitive electrochemical determination of catechol based on reduced graphene oxide decorated β-cyclodextrin nanosheet modified glassy carbon electrode, Adv. Powder Technol. In Press.
6
[7] K.G. Manjunatha, B.E.K. Swamy, H.D. Madhuchandra, K.A. Vishnumurthy, Synthesis, characterization and electrochemical studies of titanium oxide nanoparticle modified carbon paste electrode for the determination of paracetamol in presence of adrenaline, Chem. Data Collect. 31 (2021) 100604.
7
[8] M. Yang, H. Guo, L. Sun, N. Wu, M. Wang, F. Yang, T. Zhang, J. Zhang, Z. Pan, W. Yang, Simultaneous Electrochemical Detection of Hydroquinone and Catechol Using MWCNT-COOH/CTF-1 Composite Modified Electrode, Colloids Surfaces A Physicochem. Eng. Asp. 625 (2021) 126917.
8
[9] M. Haroon, I. Abdulazeez, T.A. Saleh, A.A. Al-Saadi, Electrochemically modulated SERS detection of procaine using FTO electrodes modified with silver-decorated carbon nanosphere, Electrochim. Acta. 387 (2021) 138463.
9
[10] M. Dib, A. Moutcine, H. Ouchetto, A. Chtaini, A. Hafid, M. Khouili, New efficient modified carbon paste electrode by Fe2O3@Ni/Al-LDH magnetic nanocomposite for the electrochemical detection of mercury, Inorg. Chem. Commun. (2021) 108624.
10
[11] M.D. Meti, J.C. Abbar, J. Lin, Q. Han, Y. Zheng, Y. Wang, J. Huang, X. Xu, Z. Hu, H. Xu, Nanostructured Au-graphene modified electrode for electrosensing of chlorzoxazone and its biomedical applications, Mater. Chem. Phys. 266 (2021).
11
[12] G. Boopathy, M. Keerthi, S.-M. Chen, S. Meenakshi, M.J. Umapathy, Molybdenum trioxide embedded graphitic carbon nitride sheets modified electrode for caffeine sensing in green tea and coffee powder, Mater. Chem. Phys. 269 (2021) 124735.
12
[13] K. Settu, Y.-C. Lai, C.-T. Liao, Carbon nanotube modified laser-induced graphene electrode for hydrogen peroxide sensing, Mater. Lett. 300 (2021) 130106.
13
[14] S. Vinoth, M. Govindasamy, S.F. Wang, A.A. Alothman, R.A. Alshgari, Surface engineering of roselike lanthanum molybdate electrocatalyst modified screen-printed carbon electrode for robust and highly sensitive sensing of antibiotic drug, Microchem. J. 164 (2021) 106044.
14
[15] R. Pillai, D. Sharma, C. Sarika, I.C. Lekshmi, Electrochemical detection of 1,2-Benzenediol using NiO nanocrystal modified graphite based PEEK electrodes, Mater. Today Proc. 1 (2021) 1–5.
15
[16] B. Habibi, A. Pashazadeh, L. Ali Saghatforoush, Zn-mesoporous metal-organic framework incorporated with copper ions modified glassy carbon electrode: Electrocatalytic oxidation and determination of amoxicillin, Microchem. J. 164 (2021) 106011.
16
[17] P.S. Ganesh, G. Shimoga, S.Y. Kim, S.H. Lee, S. Kaya, R. Salim, Quantum chemical studies and electrochemical investigations of pyrogallol red modified carbon paste electrode fabrication for sensor application, Microchem. J. 167 (2021) 106260.
17
[18] T.M. Lima, P.I. Soares, L.A. do Nascimento, D.L. Franco, A.C. Pereira, L.F. Ferreira, A novel electrochemical sensor for simultaneous determination of cadmium and lead using graphite electrodes modified with poly(p-coumaric acid), Microchem. J. 168 (2021) 106406.
18
[19] S. Ren, J. Zeng, Z. Zheng, H. Shi, Perspective and application of modified electrode material technology in electrochemical voltammetric sensors for analysis and detection of illicit drugs, Sensors Actuators A Phys. 329 (2021) 112821.
19
[20] A.H. Oghli, A. Soleymanpour, Ultrasensitive electrochemical sensor for simultaneous determination of sumatriptan and paroxetine using molecular imprinted polymer/sol-gel/polyoxometalate/rGO modified pencil graphite electrode, Sensors Actuators B Chem. 344 (2021) 130215.
20
[21] A. Wong, A.M. Santos, R. da Fonseca Alves, F.C. Vicentini, O. Fatibello-Filho, M. Del Pilar Taboada Sotomayor, Simultaneous determination of direct yellow 50, tryptophan, carbendazim, and caffeine in environmental and biological fluid samples using graphite pencil electrode modified with palladium nanoparticles, Talanta. 222 (2021).
21
[22] C. Núñez, J.J. Triviño, V. Arancibia, A electrochemical biosensor for As(III) detection based on the catalytic activity of Alcaligenes faecalis immobilized on a gold nanoparticle–modified screen–printed carbon electrode, Talanta. 223 (2021) 121702.
22
[23] S. Tajik, H. Beitollahi, H.W. Jang, M. Shokouhimehr, A screen printed electrode modified with Fe3O4@polypyrrole-Pt core-shell nanoparticles for electrochemical detection of 6-mercaptopurine and 6-thioguanine, Talanta. 232 (2021) 122379.
23
[24] J.-W. QU, P. SONG, X. GONG, M.-B. RUAN, W.-L. XU, Electroanalysis of Iron in Groundwater by Defective Carbon Black Modified Electrode, Chinese J. Anal. Chem. 49 (2021) e21112–e21117.
24
[25] H. Li, K. Zhou, J. Cao, Q. Wei, C. Te Lin, S.E. Pei, L. Ma, N. Hu, Y. Guo, Z. Deng, Z. Yu, S. Zeng, W. Yang, L. Meng, A novel modification to boron-doped diamond electrode for enhanced, selective detection of dopamine in human serum, Carbon N. Y. 171 (2021) 16–28.
25
[26] A. Asif, A. Heiskanen, J. Emnéus, S.S. Keller, Pyrolytic carbon nanograss electrodes for electrochemical detection of dopamine, Electrochim. Acta. 379 (2021) 138122.
26
[27] H. Amir. N. Ponpandian, C. Viswanathan, A Electrochemical Dopamine Sensor Based On RF Magnetron Sputtered TiO2/SS Thin Film Electrode, Mater. Lett. (2021) 130175.
27
[28] A. Kushwaha, G. Singh, M. Sharma, Designing of cerium phosphate nanorods decorated reduced graphene oxide nanostructures as modified electrode: An effective mode of dopamine sensing, Microchem. J. 166 (2021) 106224.
28
[29] M.S. Anantha, S.R. Kiran Kumar, D. Anarghya, K. Venkatesh, M.S. Santosh, K. Yogesh Kumar, H.B. Muralidhara, ZnO@MnO2 nanocomposite modified carbon paste electrode for electrochemical detection of dopamine, Sensors Int. 2 (2021) 100087.
29
[30] S. Siraj, C.R. McRae, D.K.Y. Wong, Hydrogenating carbon electrodes by n-butylsilane reduction to achieve an antifouling surface for selective dopamine detection, Sensors Actuators, B Chem. 327 (2021) 128881.
30
[31] X. Xiao, Z. Zhang, F. Nan, Y. Zhao, P. Wang, F. He, Y. Wang, Mesoporous CuCo2O4 rods modified glassy carbon electrode as a novel non-enzymatic amperometric electrochemical sensors with high-sensitive ascorbic acid recognition, J. Alloys Compd. 852 (2021) 157045.
31
[32] L.V. da Silva, N.D. dos Santos, A.K.A. de Almeida, D.D.E.R. dos Santos, A.C.F. Santos, M.C. França, D.J.P. Lima, P.R. Lima, M.O.F. Goulart, A new electrochemical sensor based on oxidized capsaicin/multi-walled carbon nanotubes/glassy carbon electrode for the quantification of dopamine, epinephrine, and xanthurenic, ascorbic and uric acids, J. Electroanal. Chem. 881 (2021).
32
[33] K. Chetankumar, B.E. Kumara Swamy, S.C. Sharma, Safranin amplified carbon paste electrode sensor for analysis of paracetamol and epinephrine in presence of folic acid and ascorbic acid, Microchem. J. 160 (2021) 105729.
33
[34] Q. Wang, X. Xiao, X. Hu, L. Huang, T. Li, M. Yang, Molecularly imprinted electrochemical sensor for ascorbic acid determination based on MXene modified electrode, Mater. Lett. 285 (2021) 129158.
34
[35] G.K. Jayaprakash, B.E. Kumara Swamy, S. Rajendrachari, S.C. Sharma, R. Flores-Moreno, Dual descriptor analysis of cetylpyridinium modified carbon paste electrodes for ascorbic acid sensing applications, J. Mol. Liq. 334 (2021) 116348.
35
[36] H. Vidya, B.E.K. Swamy, Voltammetric determination of dopamine in the presence of ascorbic acid and uric acid at sodium dodecyl sulphate/reduced graphene oxide modified carbon paste electrode, J. Mol. Liq. 211 (2015) 705–711.
36
[37] A.A. Rafati, A. Afraz, A. Hajian, P. Assari, Simultaneous determination of ascorbic acid, dopamine, and uric acid using a carbon paste electrode modified with multiwalled carbon nanotubes, ionic liquid, and palladium nanoparticles, Microchim. Acta. 181 (2014) 1999–2008.
37
[38] N. Soltani, N. Tavakkoli, N. Ahmadi, F. Davar, Simultaneous determination of acetaminophen, dopamine and ascorbic acid using a PbS nanoparticles Schiff base-modified carbon paste electrode, Comptes Rendus Chim. 18 (2015) 438–448.
38
[39] H. Vidya, B.E. Kumara Swamy, M. Schell, One step facile synthesis of silver nanoparticles for the simultaneous electrochemical determination of dopamine and ascorbic acid, J. Mol. Liq. 214 (2016) 298–305.
39
[40] N.F. Atta, A. Galal, Y.M. Ahmed, E.H. El-Ads, Design strategy and preparation of a conductive layered electrochemical sensor for simultaneous determination of ascorbic acid, dobutamine, acetaminophen and amlodipine, Sensors Actuators, B Chem. 297 (2019) 126648.
40
[41] D.M. Stanković, A. Samphao, B. Dojcinović, K. Kalcher, Rapid electrochemical method for the determination of L-DOPA in extract from the seeds of Mucuna Prurita, Acta Chim. Slov. 63 (2016) 220–226.
41
[42] K. Ghanbari, N. Hajheidari, ZnO-CuxO/polypyrrole nanocomposite modified electrode for simultaneous determination of ascorbic acid, dopamine, and uric acid, Anal. Biochem. 473 (2015) 53–62.
42
[43] A.C. Anithaa, N. Lavanya, K. Asokan, C. Sekar, WO3 nanoparticles based direct electrochemical dopamine sensor in the presence of ascorbic acid, Electrochim. Acta. 167 (2015) 294–302.
43