The Response Surface Methodology to Optimize the Catalytic Degradation of 4-Chloro 2-Nitro Phenol

Document Type: Original research article


1 Chemical Department, Chemical Faculty, Islamic Azad University, Tehran Central Branch, Tehran, Iran

2 Chemical Department, Chemical Faculty, Islamic Azad University ,Khoy Branch, Khoy, Iran


The catalytic degradation of 4-chloro 2-nitro phenol aromatic compound has been studied with coupled ozone-sonolysis method. The response surface methodology was used to optimize the influence of operation parameters on the catalytic degradation of 4-chloro 2-nitro phenol. In order to evaluate the influence of operation conditions in the degradation of 4-Chloro 2-Nitro Phenol, four independent variable chosen: 4-Chloro 2-Nitro Phenol concentration, mass flow rate of O3, TiO2 concentration and ultra sonic power. Analysis of variance was employed to consider main factors effects and interactive effects in the optimization of catalytic degradation of of 4-Chloro 2-Nitro Phenol. Analysis of variance results present that the model is statistically significant. The response surface methodology predictions were in agreement with the experimental values.



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