Sensitive Cysteamine Determination Using Disposable Electrochemical Sensor Based on Modified Screen Printed Electrode

Document Type: Original research article


1 Department of Chemistry, Payame Noor University, Tehran, Iran

2 Research Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran

3 Environment Department, Institute of Science and High Technology and EnvironmentalSciences, Graduate University of Advanced Technology, Kerman, Iran


In the present study, the cysteamine electrochemical features were explored by La2O3/Co3O4 nanocomposite-modified screen printed electrode (La2O3/Co3O4/SPE) using voltammetry, chronoamperometry, and differential pulse voltammetry (DPV) techniques. The synthesized La2O3/Co3O4 nanocomposite qualities were considered by SEM, FT-IR, and XRD analyses. Exploiting the modified SPE electrode with La2O3/Co3O4 nanocomposite, the cysteamine electrooxidation kinetics was significantly enhanced by reducing the anodic over-potential. The constructed La2O3/Co3O4/SPE revealed voltammetric reactions of high sensitivity for cysteamine, resulting in a highly appropriate means of trace levels cysteamine measurement. The electrooxidation peak currents for cysteamine were found to change linearly in relation to its concentrations (1.0–700.0 μM) in detection limit of 0.3 μM. La2O3/Co3O4/SPE was utilized for the cysteamine quantification in real specimens.


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