Pouran Pourhakkak; Shokoufeh Omidi; Mahdi Yarahmadi
Abstract
In this research, the results of two existing methods for synthesizing gold nanoparticles, i.e., the green and environment-friendly method and the usual chemical method called Turkovich, were compared and analyzed. In the green method, the extract of the aerial parts of the medicinal plant Mentha pulegium ...
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In this research, the results of two existing methods for synthesizing gold nanoparticles, i.e., the green and environment-friendly method and the usual chemical method called Turkovich, were compared and analyzed. In the green method, the extract of the aerial parts of the medicinal plant Mentha pulegium was used as a regenerating agent, and both methods, SEM, TEM, UV-VIS, EDX, and DLS, investigated the properties of the synthesized gold nanoparticles. The results indicated that the green synthesis of gold nanoparticles by extracting the aerial parts of the Mentha pulegium plant was smaller and more stable than the Turkevich method. SEM and TEM results show that the morphology of all nanoparticles is spherical. The size of nanoparticles synthesized by sodium citrate is 10.3 nm, and the size of nanoparticles synthesized by Mentha pulegium plant extract is 9.6 nm. The UV-VIS results show almost absorption in the region of 526 nm for gold nanoparticles synthesized by sodium citrate and absorption in the region of 421 nm for gold nanoparticles synthesized by Mentha pulegium plant extract. The synthesized gold nanoparticles had antibacterial activity against different bacteria.
Parvin Pourhakkak; Mohammad Ali Karimi; Hossein Tavallali; Pouran Pourhakkak; Mohammad Mazloum Ardakani
Abstract
A new potentiometric sensor based on a β- cyclodextrin modified carbon paste electrode (CPE) was designed for the determination of the captopril drug. The effect of various cyclodextrins (α, β and γ- cyclodextrins) and their percentage, binder agent and ion additive on the potential ...
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A new potentiometric sensor based on a β- cyclodextrin modified carbon paste electrode (CPE) was designed for the determination of the captopril drug. The effect of various cyclodextrins (α, β and γ- cyclodextrins) and their percentage, binder agent and ion additive on the potential response have been investigated and the electrode with the best potential response was found. The linear concentration range for this electrode was 7.0×10-7-1.0×10-1 M with a low detection limit of 2.0 × 10-7 M. The effect of pH and temperature on the Nernstian slope was also investigated and the optimal range was obtained. The selectivity of the captopril CPE to interfering species including Li+, K+, Ni+, Mg2+, Ca2+, Co2+, Cr2+, Cr3+, Zn2+,Mn2+, Fe2+, F-, Cl-, SO42-, C2O42- PO43-, C2O42-, ascorbic acid, uric acid, glucose, D-fructose and sucrose was determined by Separate Solution (SSM) and Matched Potential Method (MPM) methods. Finally, the proposed electrode was tested for measuring captopril in drug formulation, blood serum, and urine samples.
