In collaboration with Payame Noor University and Iranian Chemical Science and Technologies Association
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Micronization of Clozapine Particles Using Rapid Expansion of Supercritical Solution with Solid Cosolvent (RESS-SC) Process

Majid Haji Hosseini

Volume 10, Issue 2 , September 2023, , Pages 129-137

https://doi.org/10.30473/ijac.2024.70553.1287

Abstract
  The rapid expansion of a supercritical solution (RESS) process has limited commercial applicability due to the extremely low solubility of polar drugs in supercritical CO2 (sc CO2). To overcome this major limitation, a modified process of rapid expansion of supercritical solution with solid cosolvent ...  Read More