In collaboration with Payame Noor University and Iranian Chemical Science and Technologies Association

Document Type : Full research article


1 Department of Chemistry, Payame Noor University, 19395-4697 Tehran, Iran

2 Food safety and quality control department, research institute of food science and technology, Mashhad, Iran


For the first time, hollow fiber-solid liquid phase microextraction (HF-SLPME) using multiwalled carbon nanotube- ion exchange polyurethane foam (MWCNT-PUFIX) as adsorbent along with graphite furnace atomic absorption spectrometry was used to extract and measure the anticancer drug cisplatin. In this method, the nanocomposite dispersed in octanol, is located in the pores and lumen of a porous polypropylene hollow fiber, was used as the extracting phase, this method benefits from high selectivity, high sample purification and enrichment, and reducing the consumption of organic solvents. The major factors affecting the extraction efficiency were investigated. The validation of the method was assessed by linearity, limit of detection, and accuracy calculated as relative recovery percent. The calibration curve was constructed under the optimal conditions was linear in the range of 1.00-55.0 µg/mL and the detection limit was 0.5 µg/mL. This method was successfully used for analysis of biological samples and the obtained results showed that the method has good accuracy and precision.