Nourolhoda Razavi; Amene Zendegi-Shiraz; Zarrin Eshaghi
Abstract
This study considers identification and determination of phthalates esters in cosmetic samples. The dispersive solid phase extraction was used for extraction of analytes prior to high performance liquid chromatography analysis. The solid sorbent for extraction was polyethylene glycol grafted on cupric ...
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This study considers identification and determination of phthalates esters in cosmetic samples. The dispersive solid phase extraction was used for extraction of analytes prior to high performance liquid chromatography analysis. The solid sorbent for extraction was polyethylene glycol grafted on cupric oxide nanoparticles (PEG-g-CuO-NPs). This sorbent was first synthesized and characterized by scanning electron microscopy (SEM), Energy-dispersive X-ray(EDX) and fourier-transform infrared spectroscopy (FT-IR) then efficiently applied for extraction of analytes. The extraction conditions like amount of sorbent, kind and volume of desorption solvent, extraction and desorption time, and pH of sample solution were optimized. The validation of method carried out under optimum conditions. Linear ranges were 0.005-4 µgmL-1 with the coefficient correlation (R2) in the range of 0.9914-0.9962. The limits of detection (LODs) (3S/N) were 0.0025 to 0.005 µgmL-1 and acceptable repeatability’s (RSDs below 6.45%, n=5) obtained. Application of proposed method was investigated by extraction of phthalates in shampoo and body wash for babies which satisfaction results achieved.
Matina Azad Roosta; Atefeh Tamaddon; Elham Moniri
Abstract
In present work Hengam island sands were used for preparation of new magnetic nano-adsorbent. These sands have intrinsic magnetic properties due to possess specific compounds such as Fe3O4. It was modified by surface activator agent namely 3-(Glycidyloxypropyl)trimethoxysilane to produce effective nano-adsorbent. ...
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In present work Hengam island sands were used for preparation of new magnetic nano-adsorbent. These sands have intrinsic magnetic properties due to possess specific compounds such as Fe3O4. It was modified by surface activator agent namely 3-(Glycidyloxypropyl)trimethoxysilane to produce effective nano-adsorbent. After preparation of this nano-adsorbent, Its physical and chemical properties was verified using several techniques such as FTIR, TGA/DTG, XRD and SEM. Nano-adsorbent was used as a solid phase to extraction of cetirizine from aqueous solutions and then its determination was done by HPLC. Effective analytical parameters such as pH of sample solution (pH=4), dosage of nano-adsorbent (100 mg), zero charge (pHz=5), breakthrough volume (500 mL) and contact time (15 min) were evaluated and optimized. Furthermore, figures of merit parameters such as precision (RSD=1.44%), limit of detection (LOD=1.1 µg L-1) and linear dynamic range (LDR=0.01-250 mg L-1) were obtained. Also for validation the accuracy of method, amount of cetirizine in two real samples were successfully determined.
Fatemeh Nourpishe; Ali Asghar Amiri; Ali Sheibani; Masoud Reza Shishehbore
Abstract
In this study, a simple and sensitive method was developed for pre-concentration of spirotetramat (SPT) using the ionic liquid-based dispersive liquid-liquid microextraction. After extracting of SPT into 1-butyl-3-methylimidazolium hexafluorophosphate (ionic liquid), the insecticide was injected into ...
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In this study, a simple and sensitive method was developed for pre-concentration of spirotetramat (SPT) using the ionic liquid-based dispersive liquid-liquid microextraction. After extracting of SPT into 1-butyl-3-methylimidazolium hexafluorophosphate (ionic liquid), the insecticide was injected into HPLC system for determining. Under the optimum conditions, the developed method provided a linearity in the range of 0.05–2.0 µg mL-1 with R2= 0.9987, and also enrichment factor was 250. The detection limit and relative standard deviation of the developed method were 0.01 µg mL-1 and 2.7%, respectively. The proposed method was successfully applied to the pre-concentration and determination of SPT in spiked water samples with mean recoveries 94.0-96.0%.
Mohammadreza Hadjmohammadi; Maede Asadi
Volume 2, Issue 1 , March 2015, , Pages 36-42
Abstract
A simple, inexpensive and efficient method was used for extraction and determination of Fexofenadine and Levocetirizine with three–phase hollow fiber liquid-phase microextraction and high-performance liquid chromatography. Several parameters influencing the extraction recoveries such as the nature ...
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A simple, inexpensive and efficient method was used for extraction and determination of Fexofenadine and Levocetirizine with three–phase hollow fiber liquid-phase microextraction and high-performance liquid chromatography. Several parameters influencing the extraction recoveries such as the nature of organic extraction solvent, pH of donor and acceptor phases, stirring rate, extraction time and salt addition to the sample solution (donor phase) were investigated and optimized. Under the optimized conditions (toluene as organic solvent, pHdonor = 2.5, pHacceptor = 12.0, stirring rate of 1000 rpm, extraction time of 30 min, with no salt addition), extraction recoveries were 64% for Fexofenadine and 79% for Levocetirizine. A good clean-up sample with excellent linearities in the range of 1–500 ng/mL for Fexofenadine (R2=0.997) and 0.6-600 ng/mlfor Levocetirizine (R2=0.998) were obtained. The limits of detection were 0.3 ng/mL for Fexofenadine and 0.2 ng/mL for Levocetirizine.
Mohammad Reza Hadjmohammadi; Maede Asadi
Volume 1, Issue 2 , September 2014, , Pages 65-71
Abstract
The applicability of hollow fiber-based liquid phase microextraction (HF-LPME) was evaluated for the extraction and preconcentration of Loratadine prior to determination by HPLC. In order to obtain high extraction recovery, the parameters affecting the HF-LPME including type of organic phase, pH of the ...
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The applicability of hollow fiber-based liquid phase microextraction (HF-LPME) was evaluated for the extraction and preconcentration of Loratadine prior to determination by HPLC. In order to obtain high extraction recovery, the parameters affecting the HF-LPME including type of organic phase, pH of the source and receiving phases, stirring rate, extraction time and salt addition were studied and optimized. Under the optimized conditions, enrichment factor of 308 with relative standard deviation (R.S.D.%) equel 3.8% were achieved. The calibration curve was linear in the range of 0.3–600 ng/ml with good linearity (R2 = 0.9991). The limit of detection (LOD) was 0.1 ng/ml (based on S/N = 3). Finally, determination of Loratadine in human plasma was used by HF-LPME-HPLC and indicated that this method had an excellent clean-up and high recovery factor (84%) for Loratadine.
